CAS Number 89796-99-6, Aceclofenac IP BP Ph Eur EP Grade Manufacturers Exporters
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CAS Number 89796-99-6, Aceclofenac IP BP Ph Eur EP Manufacturer Exporter
For Properties Specifications of Aceclofenac Click Properties, Specifications of Aceclofenac Manufacturer.
For Uses of aaa Click Uses of Aceclofenac Manufacturer.
For For SDS MSDS Sheet of Aceclofenac Click SDS Safety Data Sheet MSDS Sheet of Aceclofenac Manufacturer.
The Properties and Specifications of Aceclofenac:
Aceclofenac BP Ph Eur Grade Specifications:
C16H13Cl2NO4 --- 354.2 CAS 89796-99-6
Action and use: Cyclo-oxygenase inhibitor; analgesic; anti-inflammatory.
DEFINITION
[[[2-[(2,6-Dichlorophenyl)amino]phenyl]acetyl]oxy]acetic acid.
Content: 99.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent).
IDENTIFICATION
First identification: B
Second identification: A, C
A. Ultraviolet and visible absorption spectrophotometry.
B. Infrared absorption spectrophotometry.
C. Dissolve about 10 mg in 10 mL of ethanol (96 per cent). To 1 mL of the solution, add 0.2 mL of a mixture, prepared immediately before use, of equal volumes of a 6 g/L solution of potassium ferricyanide and a 9 g/L solution of ferric chloride. Allow it to stand protected from light for 5 min. Add 3 mL of a 10.0 g/L solution of hydrochloric acid. Allow to stand protected from light for 15 min. A blue colour develops and a precipitate is formed.
Related substances: To pass the test by Liquid chromatography.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
We also supply Aceclofenac IP EP Grade.
The Uses of Aceclofenac:
Aceclofenac is a nonsteroidal anti-inflammatory drug analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
The MSDS-SDS Hazard Statement of Aceclofenac:
Aceclofenac SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 15-Nov-24
1. Product Identification
Product Name & Other Names: Aceclofenac.
CAS No.: 89796-99-6
EINECS EC Code: 641-844-5
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 3) H301
Eye irritation (Category 2) H319
Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements  Toxic |
GHS Label Elements |
Signal Word: Danger
Hazard Statements:
H301: Toxic if swallowed
H319: Causes serious eye irritation.
Precautionary Statements
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310+330: IF SWALLOWED: Rinse mouth and immediately call a POISON CENTER or doctor/physician.
P303+P361+P352: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Wash with plenty of soap and water.
P304+P341+P311: IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
3. Composition/Information on Ingredients
Product Name & Other Names: Aceclofenac.
CAS No.: 89796-99-6
EINECS EC Code: 641-844-5
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, it will cause irritation. Remove the victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention.
Eye Contact: It can cause severe irritation and harm to eyes. Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Fire: Toxic fumes, hydrogen chloride, nitrogen oxides, carbon dioxide and carbon monoxide may be formed in fire.
Fire Extinguishing Media: Dry chemical, foam or carbon dioxide and water spray. Avoid solid water jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Sweep and shovel and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
Large Spill: Contain spilled material. Sweep and shovel and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Avoid dust/mist formation. Keep away from heat.
7. Handling and Storage
Precautions for safe handling: Toxic. Do not swallow. Apply according to good manufacturing and industrial hygiene practices. Avoid prolonged or repeated exposure. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Store away from foodstuffs. Storage: Room temperature.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White to off-white powder or crystals.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting Point: 149C to 153C literature.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Practically insoluble in water. Freely soluble in acetone.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Toxic fumes, hydrogen chloride, nitrogen oxides, carbon dioxide and carbon monoxide may be formed in fire.
Hazardous Polymerization: Not likely.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flames, moisture, light, ignition sources and incompatibles.
11. Toxicological Information
Oral rat LD50: 130 mg/kg.
Carcinogenicity: Not reported as carcinogen by any agency.
Reproductive Toxicity: No data found.
Developmental Effects: No data found.
Teratogenicity: No data found.
12. Ecological Information
Persistence and Degradability: No data found.
Bioaccumulation/ Accumulation: No data found.
Mobility: No data found.
Results of PBT and vPvB assessment: No data found.
Environmental Toxicity: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control norms.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe:
UN Number: UN 2811
Proper shipping name: TOXIC SOLIDS, ORGANIC, N.O.S. (ACECLOFENAC)
Class: 6.1, Packing group: III.
IMDG/IMO & IATA/ICAO:
UN Number: UN 2811
Proper shipping name: TOXIC SOLIDS, ORGANIC, N.O.S. (ACECLOFENAC)
Class: 6.1, Packing group: III.
15. Regulatory Information
USA:
SARA 311/312: See section2.
California Prop 65: Not listed.
Section 16 - Additional Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Aceclofenac Structure
CAS Number 89796-99-6, Aceclofenac Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 11-dec-24
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