CAS Number 56392-17-7, Metoprolol Tartrate USP IP EP BP Ph Eur Grade Manufacturers Exporters
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CAS Number 56392-17-7, Metoprolol Tartrate USP IP EP BP Ph Eur Manufacturer Exporter
For Properties Specifications of Metoprolol Tartrate Click Properties, Specifications of Metoprolol Tartrate Manufacturer.
For Uses of Metoprolol Tartrate Click Uses of Metoprolol Tartrate Manufacturer.
For For SDS MSDS Sheet of aaMetoprolol Tartratea Click SDS Safety Data Sheet MSDS Sheet of Metoprolol Tartrate Manufacturer.
The Properties and Specifications of Metoprolol Tartrate:
Metoprolol Tartrate USP Grade Specifications:
(C15H25NO3)2-C4H6O6 684.81
2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (±)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt);
(±)-1-(Isopropylamino)-3-[p-(2-methoxyethyl)phenoxy]-2-propanol l-(+)-tartrate (2:1) (salt)
1-(Isopropylamino)-3-[p-(2-methoxyethyl)phenoxy]-2-propanol (2:1) dextro-tartrate salt CAS 56392-17-7
UNII: W5S57Y3A5L
UNII: GEB06NHM23
DEFINITION
Metoprolol Tartrate contains NLT 98.0% and NMT 102.0% of metoprolol tartrate [(C15H25NO3)2-C4H6O6], calculated on the dried basis.
IDENTIFICATION
A. Infrared Absorption.
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
Residue on Ignition: NMT 0.1%
Organic Impurities: To pass the test.
Optical Rotation, Specific Rotation:
Sample solution: 20 mg/mL in water
Acceptance criteria: +6.5° to +10.5° (t = 20°)
pH: 6.0–7.0 in 100 mg/mL of Metoprolol Tartrate in water
Loss on Drying: Dry a sample in a vacuum at 60C for 4 h. Acceptance criteria: NMT 0.5%
Metoprolol Tartrate BP Ph Eur Grade Specifications:
C34H56N2O12 --- 685 CAS 56392-17-7
DEFINITION
Bis[(2RS)-1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol] (2R,3R)-2,3-dihydroxybutanedioate.
Content: 99.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals.
Solubility: Very soluble in water, freely soluble in ethanol (96 per cent).
It shows polymorphism.
IDENTIFICATION
A. Specific optical rotation.
B. Infrared absorption spectrophotometry.
TESTS
Solution S: Dissolve 0.500 g in carbon dioxide-free water and dilute to 25.0 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 6.0 to 7.0 for solution S.
Specific optical rotation: + 7.0 to + 10.0 (dried substance), determined on solution S.
Impurities M, N, O: To pass the test by Thin-layer chromatography.
Related substances: To pass the test by Liquid chromatography.
We also supply Metoprolol Tartrate IP EP Grade.
The Uses of Metoprolol Tartrate:
Metoprolol Tartrate is used in managing hypertension, angina, and other cardiovascular conditions while maintaining a high level of safety and tolerability.The MSDS-SDS Hazard Statement of Metoprolol Tartrate:
Metoprolol Tartrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 09-Nov-24
1. Product Identification
Product Name & Other Names: Metoprolol Tartrate.
CAS Number: 56392-17-7
EINECS EC Number: 260-148-9
Intended Use: Industrial Manufacturing.
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Reproductive toxicity Category 2, H361
Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements  Health Hazard |
Signal Words: Danger
Hazard Statements:
H361: Suspected of damaging fertility or the unborn child.
Precautionary Statements:
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get medical advice/attention if you feel unwell.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
3. Composition/Information on Ingredients
Product Name & Other Names: Metoprolol Tartrate.
CAS Number: 56392-17-7
EINECS EC Number: 260-148-9
4. First Aid Measures
Inhalation: Remove affected person to fresh air; if normal breathing has not returned within a few minutes after exposure, get medical attention.
Skin: Remove contaminated clothing; wash affected area with soap and water; launder contaminated clothing before reuse. Seek medical attention.
Eyes: Immediately, flush eyes for 15 minutes in clear running water while holding eyelids open; seek medical attention immediately.
Ingestion: Drink two glasses of water followed by milk, milk of magnesia or other non-alcoholic liquids; Do not induce vomiting; seek medical attention immediately.
5. Fire Fighting Measures
Flammable Limits: No unusual fire or explosion hazards noted. However, it will burn at high temperature.
General Hazards: Contact with eyes causes immediate severe irritation of the eye and eyelids. Product will support combustion.
Extinguishing Media: Carbon dioxide, water fog, dry chemical, chemical foam.
Organics solids, may be ignitable. Avoid solid water jet as it may spread the fire.
Fire & Explosion Hazard: May evolve toxic fumes, oxides of carbon (COx), oxides of nitrogen (NOx) under fire conditions.
Hazardous Combustion Products: Products of combustion include smoke, toxic fumes, oxides of carbon to include carbon monoxide, nitrogen oxides.
Specific Methods: Cool containers exposed to flames with water until well after the fire is out.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: It may support combustion. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Provide appropriate exhaust ventilation at places where dust is formed. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agent. Keep this and other chemicals out of reach of children. Storage: Room temperature in tight, light-resistant containers.
8. Exposure Controls/Personal Protection
Engineering Controls: The use of local exhaust ventilation is recommended to control emissions near the source. Provide mechanical ventilation of confined spaces. Use corrosion-resistant, explosion-proof ventilation equipment.
Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White to almost white powder to crystal.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting/Freezing Point: 120C to 124C.
Initial boiling point and boiling range: 399C.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility in Water: Soluble in water, methanol and chloroform.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable at normal temperatures and operating conditions.
Conditions to Avoid: Avoid excessively high temperatures and contact with strong oxidizing agents.
Incompatibilities: Oxidizing Agent.
Decomposition: Decomposition yields toxic fumes, oxides of carbon (COx), oxides of nitrogen (NOx.
Polymerization: Polymerization will not occur.
11. Toxicological Information
Toxic if swallowed.
Toxicity Data:
LD50 Oral - Rat - >5000 mg/kg
Reproduction: Suspected of damaging fertility or the unborn child.
Carcinogenicity: Not listed as a human carcinogen by OSHA, IARC, ACGIH & NTP.
12. Ecological Information
Toxicity to fish: No data found.
Results of PBT and vPvB assessment: No data found.
Persistence and degradability: Unlikely to persist due to water solubility.
Mobility in soil: Likely to be mobile due to water solubility.
Bioaccumulative potential: No data found.
Mobility: Likely to be mobile due to water solubility.
13. Disposal Considerations
Dispose of it in accordance with Local, State, and Federal Regulations. Follow all the pollution control norms.
14. Transport Information
DOT USA & ADR/RID Europe: Not controlled.
IATA & IMDG: Not controlled.
15. Regulatory Information
No additional data found.
Section 16 - Additional Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Metoprolol Tartrate Structure
CAS Number 56392-17-7, Metoprolol Tartrate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 19-nov-24
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