CAS Number 6100-05-6 & 866-84-2, Potassium Citrate Anhydrous Monohydrate USP IP BP Ph Eur Analytical Reagent FCC Food Grade Manufacturers Exporters
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CAS Number 6100-05-6 & 866-84-2, Potassium Citrate Anhydrous Monohydrate Manufacturer Exporter
For Properties Specifications of Potassium Citrate Anhydrous Monohydrate Click Properties, Specifications of Potassium Citrate Anhydrous Monohydrate Manufacturer.
For Uses of Potassium Citrate Anhydrous Monohydrate Click Uses of Potassium Citrate Anhydrous Monohydrate Manufacturer.
For For SDS MSDS Sheet of Potassium Citrate Anhydrous Monohydrate Click SDS Safety Data Sheet MSDS Sheet of Potassium Citrate Anhydrous Monohydrate Manufacturer.
The Properties and Specifications of Potassium Citrate Anhydrous Monohydrate:
Potassium Citrate USP Grade Specifications
C6H5K3O7-H2O 324.41
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt, monohydrate.
Tripotassium citrate monohydrate CAS 6100-05-6
Anhydrous 306.40 CAS 866-84-2
Potassium Citrate contains not less than 99.0 percent and not more than 100.5 percent of C6H5K3O7, calculated on the dried basis.
Identification: A solution (1 in 10) responds to the tests for Potassium and for Citrate.
Alkalinity: A solution of 1.0 g in 20 mL of water is alkaline to litmus, but after the addition of 0.20 mL of 0.10 N sulfuric acid, no pink color is produced by the addition of 1 drop of PhPh TS.
Loss on drying: Dry it at 180 for 4 hours: it loses between 3.0% and 6.0% of its weight.
Tartrate: To a solution of 1 g in 1.5 mL of water in a test tube add 1 mL of 6 N acetic acid, and scratch the walls of the test tube with a glass rod: no crystalline precipitate is formed.
Heavy metals: Dissolve 2 g in 25 mL of water, and proceed as directed for Test Preparation, except to use glacial acetic acid to adjust the pH: the limit is 0.001%.
Potassium Citrate BP Ph Eur Grade Specifications
C6H5K3O7,H2O -- 324.4 -- CAS 6100-05-6
DEFINITION
Potassium citrate contains not less than 99.0 per cent and not more than the equivalent of 101.0 per cent of tripotassium 2-hydroxypropane-1,2,3-tricarboxylate, calculated with reference to the anhydrous substance.
CHARACTERS
A white, granular powder or transparent crystals, hygroscopic, very soluble in water, practically insoluble in alcohol.
IDENTIFICATION
A. To 1 ml of solution S (see Tests) add 4 ml of water. The solution gives the reaction of citrates.
B. 0.5 ml of solution S gives reaction of potassium.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 10 ml of solution S add 0.1 ml of PhPh solution. Not more than 0.2 ml of 0.1 M hydrochloric acid or 0.1 M sodium hydroxide is required to change the colour of the indicator.
Readily carbonizable substances: To 0.20 g of the powdered substance to be examined add 10 ml of sulphuric acid and heat in a water-bath at 90 ± 1C for 60 min. Cool rapidly. The solution is not more intensely coloured than reference solution.
Chlorides: Dilute 10 ml of solution S to 15 ml with water. The solution complies with the limit test for chlorides (50 ppm).
Oxalates: Dissolve 0.50 g in 4 ml of water, add 3 ml of hydrochloric acid and 1 g of granulated zinc and heat on a water-bath for 1 min. Allow to stand for 2 min, decant the liquid into a test-tube containing 0.25 ml of a 10 g/l solution of phenylhydrazine hydrochloride and heat to boiling. Cool rapidly, transfer to a graduated cylinder and add an equal volume of hydrochloric acid and 0.25 ml of potassium ferricyanide solution. Shake and allow to stand for 30 min. Any pink colour in the solution is not more intense than that in a standard prepared at the same time and in the same manner using 4 ml of a 0.05 g/l solution of oxalic acid (300 ppm).
Sulphates: To 10 ml of solution S add 2 ml of hydrochloric acid and dilute to 15 ml with distilled water. The solution complies with the limit test for sulphates (150 ppm).
Heavy metals: 12 ml of solution S complies with limit test A for heavy metals (10 ppm).
Sodium: Not more than 0.3 per cent of Na, determined by atomic emission spectrometry.
Water: 4.0 per cent to 7.0 per cent, determined on 0.500 g by the semi-micro determination of water. After adding the substance to be examined, stir for 15 min before titrating.
Potassium Citrate IP Grade
Potassium citrate IP grade is also offered.
Potassium Citrate FCC Food Grade Specifications
Tripotassium Citrate
KOOCCH2C(OH)(COOK)CH2COOK-H2O
C6H5K3O7-H2O Formula weight 324.41
INS: 332(ii) CAS 6100-05-6
DESCRIPTION
Potassium Citrate occurs as transparent crystals or as a white, granular powder. It is deliquescent when exposed to moist air. One gram dissolves in about 0.5 mL of water. It is almost insoluble in alcohol.
Function: Buffer; sequestrant; stabilizer.
REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for Potassium and for Citrate.
Assay: Not less than 99.0% and not more than 100.5% of C6H5K3O7 after drying.
Alkalinity: A 1:20 aqueous solution is alkaline to litmus, but after the addition of 0.2 mL of 0.1 N sulfuric acid to 10 mL of this solution, no pink color appears after the addition of 1 drop of PhPh TS.
Lead: Not more than 2 mg/kg.
Loss on Drying: Between 3.0% and 6.0%.
The Uses of Potassium Citrate Anhydrous Monohydrate:
Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. It is also used to prevent kidney stones that may occur with gout. Potassium citrate is a urinary alkalinizer. It is also a mineral supplement used to treat or prevent low amounts of potassium in the blood.
The MSDS-SDS Hazard Statement of Potassium Citrate Anhydrous Monohydrate:
Potassium Citrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 16-Jan-23
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Potassium citrate monohydrate or Tripotassium citrate.
CAS#: 6100-05-6
EINECS EC Number: 231-905-0
Molecular Weight: 324.41
Chemical Formula: C6H5K3O7.H2O
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Potassium citrate monohydrate or Tripotassium citrate.
CAS#: 6100-05-6
EINECS EC Number: 231-905-0
Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eye Contact: Wash thoroughly with running water. Get medical advice if irritation develops.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove and Clean contaminated clothing and shoes. Get medical attention.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Get medical attention.
Inhalation: If inhaled, remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.
Serious Inhalation: Not available.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt, or waistband.
Section 5: Fire and Explosion Data
Flammability of the Product: Potassium citrate may be combustible at high temperature.
Products of Combustion: These products are carbon oxides (CO, CO2). Some metallic oxides.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Do not use water jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow evacuating as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
Section 9: Physical and Chemical Properties
Appearance: White solid.
Odor: Not available.
Odor threshold: Not available.
pH (1% soln/water): 9 [Basic.]
Relative density: around 1.98
Melting Point: Decomposition temperature: 180C (356F)
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Solubility: Easily soluble in cold water.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: Stable.
Incompatibility with various substances: Strong oxidizing agents.
Corrosivity: Non-corrosive in presence of glass.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity to fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13: Disposal Considerations
Waste Disposal: To be done as per legal requirement.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IMDG/IMO & IATA/ICAO: Not controlled.
Section 15: Other Regulatory Information
USA:
SARA 311/312: See section 2.
California Proposition 65: Not listed.
DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
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Potassium Citrate Anhydrous Monohydrate Structure
CAS Number 6100-05-6 & 866-84-2, Potassium Citrate Anhydrous Monohydrate Manufacturer Exporter
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