CAS Number 3344-18-1 & 153531-96-5, Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate USP NF BP Ph Eur Analytical Reagent FCC Food Grade Manufacturers Exporters
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CAS Number 3344-18-1 & 153531-96-5, Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Manufacturer Exporter
For Properties Specifications of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Click Properties, Specifications of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Manufacturer.
For Uses of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Click Uses of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Manufacturer.
For For SDS MSDS Sheet of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Click SDS Safety Data Sheet MSDS Sheet of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Manufacturer.
The Properties and Specifications of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate:
Magnesium Citrate USP Grade Specifications
C12H10Mg3O14 -- 451.11
1,2,3-Propanetricarboxylic acid, hydroxy-, magnesium salt (2:3).
Magnesium citrate (3:2) CAS Number 3344-18-1
Magnesium Citrate contains not less than 14.5 percent and not more than 16.4 percent of magnesium (Mg), calculated on the dried basis.
Labeling: Magnesium Citrate that loses not more than 2.0% of its weight in the test for Loss on drying may be labeled as Anhydrous Magnesium Citrate.
Identification:
A: A solution (10 mg per mL) responds to the tests for Magnesium.
B: A solution (80 mg per mL) responds to the tests for Citrate.
pH: between 5.0 and 9.0, in a suspension (50 mg per mL).
Loss on drying: Dry 1 g in a mechanical convection oven at 135 for 16 hours, then to constant weight: it loses not more than 29% of its weight, except that where it is labeled as anhydrous, it loses not more than 2.0% of its weight.
Chloride: A 300-mg portion shows no more chloride than corresponds to 0.20 mL of 0.020 N hydrochloric acid (0.05%).
Sulfate: A 100-mg portion shows no more sulfate than corresponds to 0.20 mL of 0.020N sulfuric acid (0.2%).
Arsenic: 3 6g per g.
Heavy metals: Dissolve 0.4 g in 25 mL of water, and proceed as directed for Test Preparation, except to use glacial acetic acid to adjust the pH: the limit is 50 6g per g.
Iron: Boil 50 mg with 5 mL of 2 N nitric acid for 1 minute. Cool, dilute with water to 45 mL, add 2 mL of hydrochloric acid, and mix: the limit is 200 6g per g.
Limit of calcium: the limit is 1.0%, calculated on the dried basis.
Anhydrous Magnesium Citrate BP Ph Eur Grade Specifications
Mg3(C6H5O7)2 --- 451.1 --- CAS 3344-18-1
Ph Eur
DEFINITION
Trimagnesium bis(2-hydroxypropane-1,2,3-tricarboxylate).
Content: 15.0 per cent to 16.5 per cent of Mg (dried substance).
CHARACTERS
Appearance: White or almost white, fine, slightly hygroscopic powder.
Solubility: Soluble in water, practically insoluble in ethanol (96 per cent). It dissolves in dilute hydrochloric acid.
IDENTIFICATION
A. It gives the reaction of citrates.
B. It gives the reaction of magnesium.
C. pH (see Tests).
D. Loss on drying (see Tests).
TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water R, heating at 60C, cool and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is not more opalescent than reference suspension and not more intensely coloured than reference solutions.
pH: 6.0 to 8.5 for solution S.
Oxalates: Maximum 280 ppm.
Sulfates: Maximum 0.2 per cent.
Calcium: Maximum 0.2 per cent.
Iron: Maximum 100 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 3.5 per cent, determined on 1.000 g by drying in an oven at 180±10C for 5 h.
Magnesium Citrate Dodecahydrate BP Ph Eur Grade Specifications
Mg3(C6H5O7)2,xH2O --- 451.1 (anhydrous substance)
with x ≈ 12
Ph Eur
DEFINITION
Trimagnesium bis(2-hydroxypropane-1,2,3-tricarboxylate) dodecahydrate.
Content: 15.0 per cent to 16.5 per cent of Mg (dried substance).
CHARACTERS
Appearance: White or almost white, fine powder.
Solubility: Sparingly soluble in water, practically insoluble in ethanol (96 per cent). It dissolves in dilute hydrochloric acid.
IDENTIFICATION
A. It gives the reaction of citrates.
B. It gives the reaction of magnesium.
C. Loss on drying (see Tests).
TESTS
Solution S: Dissolve 2.5 g in 15 mL of dilute hydrochloric acid with heating. Cool and dilute to 100 mL with distilled water.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 6.0 to 8.5.
Oxalates: Maximum 280 ppm.
Sulfates: Maximum 0.2 per cent.
Calcium: Maximum 0.2 per cent.
Iron: Maximum 100 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: 29.0 per cent to 36.0 per cent, determined on 1.000 g by drying in an oven at 180±10C for 5 h.
Magnesium Citrate Nonahydrate BP Ph Eur Grade Specifications
Mg3(C6H5O7)2,9H2O --- 613 --- CAS Number 153531-96-5
Ph Eur
DEFINITION
Trimagnesium bis(2-hydroxypropane-1,2,3-tricarboxylate) nonahydrate.
Content: 15.0 per cent to 16.5 per cent of Mg (dried substance).
CHARACTERS
Appearance: White or almost white, fine powder.
Solubility: Sparingly soluble in water, practically insoluble in ethanol (96 per cent). It dissolves in dilute hydrochloric acid.
IDENTIFICATION
A. It gives the reaction of citrates.
B. It gives the reaction of magnesium (2.3.1).
C. Loss on drying (see Tests).
TESTS
Solution S: Dissolve 2.5 g in 15 mL of dilute hydrochloric acid with heating. Cool and dilute to 100 mL with distilled water.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 6.0 to 8.5.
Oxalates: Maximum 280 ppm.
Sulfates: Maximum 0.2 per cent.
Calcium: Maximum 0.2 per cent.
Iron: Maximum 100 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: 24.0 to 28.0 per cent, determined on 1.000 g by drying in an oven at 180±10C for 5 h.
The Uses of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate:
Magnesium citrate is used to treat occasional constipation on a short-term basis. Magnesium citrate is in a class of medications called saline laxatives. It works by causing water to be retained with the stool. This increases the number of bowel movements and softens the stool so it is easier to pass.
The MSDS-SDS Hazard Statement of Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate:
Magnesium Citrate SDS, Safety Data Sheet
MSDS Sheet Material Safety Data Sheet
Magnesium Citrate Anhydrous MSDS 13-Jan-23
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Magnesium citrate anhydrous.
Synonym: Trimagnesium Dicitrate; Citric Acid, Magnesium Salt (2:3); 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, magnesium salt (2:3); Citramag
CAS #: 3344-18-1
EINECS EC Number: 222-093-9
Molecular Weight: 451.13 x H20
Chemical Formula: C12-H10-Mg3-O14
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Magnesium citrate anhydrous.
CAS #: 3344-18-1
EINECS EC Number: 222-093-9
Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eye Contact: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Inhalation: If inhaled, remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do no induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing and get medical attention.
Section 5: Fire and Explosion Data
Flammability of the Product: Magnesium Citrate may be combustible at high temperature.
Products of Combustion: These products are carbon oxides (CO, CO2). Some metallic oxides.
Fire Hazards in Presence of Various Substances:
Slightly flammable to flammable in presence of heat.
Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances: Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks.
Fire Fighting Media and Instructions: Use Dry chemical powder. Use water spray, fog, or foam.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
Section 9: Physical and Chemical Properties
Appearance: Fine white granular solid, crystalline powder.
Odor: Odorless.
Odor threshold: Not available.
pH (1% soln/water): 3-5.
Relative density: Not available.
Melting Point: 184C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Partially soluble in cold water.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: Stable under ordinary conditions of storage and use.
Conditions of Instability: Excess heat, dust generation, incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents.
Corrosivity: Non-corrosive in presence of glass.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals:
LD50: Not available.
LC50: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity Data: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13: Disposal Considerations
Waste Disposal: Waste of Magnesium Citrate must be disposed of in accordance with environmental control regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IMDG/IMO: Not controlled.
IATA/ICAO: Not controlled.
Section 15: Other Regulatory Information
USA Regulations:
California Proposition 65: This product does not contain any substances known to the state of California to cause cancer, developmental and/or reproductive harm.
DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Structure
CAS Number 3344-18-1 & 153531-96-5, Magnesium Citrate Anhydrous Nonahydrate Dodecahydrate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 1-feb-23
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