CAS Number 5785-44-4, Tricalcium Citrate or Calcium Citrate Tetrahydrate USP BP Ph Eur FCC Food Grade Manufacturers Exporters
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CAS Number 5785-44-4, Tricalcium Citrate or Calcium Citrate Tetrahydrate Manufacturer Exporter
For Properties Specifications of Tricalcium Citrate or Calcium Citrate Tetrahydrate Click Properties, Specifications of Tricalcium Citrate or Calcium Citrate Tetrahydrate Manufacturer.
For Uses of Tricalcium Citrate or Calcium Citrate Tetrahydrate Click Uses of Tricalcium Citrate or Calcium Citrate Tetrahydrate Manufacturer.
For For SDS MSDS Sheet of Tricalcium Citrate or Calcium Citrate Tetrahydrate Click SDS Safety Data Sheet MSDS Sheet of Tricalcium Citrate or Calcium Citrate Tetrahydrate Manufacturer.
The Properties and Specifications of Tricalcium Citrate or Calcium Citrate Tetrahydrate:
Calcium Citrate USP Grade Specifications
C12H10Ca3O14-4H2O 570.49
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt (2:3), tetrahydrate.
Calcium citrate (3:2), tetrahydrate CAS 5785-44-4
Calcium Citrate contains four molecules of water of hydration. When dried at 150C to constant weight, it contains not less than 97.5 percent and not more than 100.5 percent of Ca3(C6H5O7)2.
Identification:
A: Dissolve 0.5 g in a mixture of 10 mL of water and 2.5 mL of 2 N nitric acid. Add 1 mL of mercuric sulfate TS, heat to boiling, and add 1 mL of potassium permanganate TS: a white precipitate is formed.
B: Ignite completely 0.5 g at as low a temperature as possible, cool, and dissolve the residue in a mixture of 10 mL of water and 1 mL of glacial acetic acid. Filter, and add 10 mL of ammonium oxalate TS to the filtrate: a voluminous white precipitate is formed, and it is soluble in hydrochloric acid.
Loss on drying: Dry it at 150 for 4 hours: it loses between 10.0% and 13.3% of its weight.
Arsenic: the limit is 3 µg per g.
Limit of fluoride: the limit is 0.003%.
Limit of acid-insoluble substances: Dissolve 5 g by heating with a mixture of 10 mL of hydrochloric acid and 50 mL of water for 30 minutes: the residue so obtained, filtered, washed, and dried at 105 for 2 hours, weighs not more than 10 mg (0.2%).
Lead: the limit is 0.001%.
Heavy metals: the limit is 0.002%.
Calcium Citrate FCC Food Grade Specifications
Tricalcium Citrate
CH2(COO)C(OH)(COO)CH2COO2Ca3
Ca3(C6H5O7)2-4H2O Formula weight 570.50
INS: 333 CAS 5785-44-4
DESCRIPTION
Calcium Citrate occurs as a fine, white powder. It is very slightly soluble in water, but it is insoluble in alcohol.
REQUIREMENTS
Identification:
A. Dissolve 500 mg of sample in 10 mL of water and 2.5 mL of 1.7 N nitric acid, add 1 mL of mercuric sulfate TS, heat to boiling, and then add potassium permanganate. A white precipitate forms.
B. Completely ignite 500 mg of sample at as low a temperature as possible, cool, and dissolve the residue in a mixture of 10 mL of water and 1 mL of glacial acetic acid. Filter, and add 10 mL of ammonium oxalate TS to the filtrate. A voluminous, white precipitate forms that is soluble in hydrochloric acid.
Assay: Not less than 97.5% and not more than 100.5% of Ca3(C6H5O7)2 after drying.
Fluoride: Not more than 0.003%.
Lead: Not more than 2 mg/kg.
Loss on Drying: Between 10.0% and 14.0%.
The Uses of Tricalcium Citrate or Calcium Citrate Tetrahydrate:
It may be used to treat conditions caused by low calcium levels such as bone loss, weak bones, decreased activity of the parathyroid gland, and a certain muscle disease. Calcium citrate is used to prevent and to treat calcium deficiencies. Calcium citrate is an over-the-counter (OTC) calcium supplement. It is commonly used as a food additive (E333), usually as a preservative, but sometimes for flavor.
The MSDS-SDS Hazard Statement of Tricalcium Citrate or Calcium Citrate Tetrahydrate:
Calcium Citrate Tetrahydrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 07-Jan-22
Section 1: Chemical Product and Company Identification
Product Name & Other Trade Names: Calcium Citrate Tetrahydrate
Synonym: 1,2,3-propane tricarboxylic acid 2-hydroxy calcium salt, tetrahydrate / 2-hydroxy-1,2,3-propane tricarboxylic acid calcium salt, tetrahydrate / calcium citrate (3:2), tetrahydrate / limecitrate, tetrahydrate.
CAS Number: 5785-44-4
EINECS EC Code: 212-391-7
Chemical Formula: Ca3(C6H5O7)2-4H2O (tetrahydrate)
Molecular Weight: 570.49 g/mol (tetrahydrate) 498.43 g/mol (anhydrous)
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Trade Names: Calcium Citrate Tetrahydrate
Synonym: 1,2,3-propane tricarboxylic acid 2-hydroxy calcium salt, tetrahydrate / 2-hydroxy-1,2,3-propane tricarboxylic acid calcium salt, tetrahydrate / calcium citrate (3:2), tetrahydrate / limecitrate, tetrahydrate.
CAS Number: 5785-44-4
EINECS EC Code: 212-391-7
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Notes to Physician: Treat symptomatically.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Products of Combustion: Calcium oxide, Fumes and Oxides of carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and acids.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
Section 9: Physical and Chemical Properties
Appearance: White to off-white crystals or powder.
Odor: Odorless.
Odor threshold: Not available.
pH (5% soln/water): 5 to 6.
Relative density: around 2.32
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature : 100 - 120 °C
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Practically insoluble in cold water.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: It is stable.
Conditions of instability: Incompatible materials
Incompatibility with various substances: Oxidizing agents, acids. Heat.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals: No acute toxicity information is available for this product.
Carcinogenic Effects: Not a reported carcinogen by IARC NTP ACGIH OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Ecotoxicity: The product is not considered harmful to aquatic organisms or to cause long-term adverse effects in the environment. Not dangerous for the ozone layer.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT USA & ADR/RID Europe: Not controlled.
IMDG: Not controlled.
IATA: Not controlled.
Section 15: Other Regulatory Information
USA Regulations:
SARA 311/312 Hazardous Categorization: None
California Proposition 65: This product does not contain any Proposition 65 chemicals
DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
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Tricalcium Citrate or Calcium Citrate Tetrahydrate Structure
CAS Number 5785-44-4, Tricalcium Citrate or Calcium Citrate Tetrahydrate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 15-nov-24
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