CAS Number 20123-80-2, Calcium Dobesilate Monohydrate BP Ph Eur EP Grade Manufacturers Exporters
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CAS Number 20123-80-2, Calcium Dobesilate Monohydrate BP Ph Eur EP Manufacturer Exporter
For Properties Specifications of Calcium Dobesilate Monohydrate Click Properties, Specifications of Calcium Dobesilate Monohydrate Manufacturer.
For Uses of Calcium Dobesilate Monohydrate Click Uses of Calcium Dobesilate Monohydrate Manufacturer.
For For SDS MSDS Sheet of Calcium Dobesilate Monohydrate Click SDS Safety Data Sheet MSDS Sheet of Calcium Dobesilate Monohydrate Manufacturer.
The Properties and Specifications of Calcium Dobesilate Monohydrate:
Calcium Dobesilate Monohydrate BP Ph Eur Grade Specifications
Ph. Eur.
C12H10CaO10S2-H2O --- 436.4 --- CAS 20123-80-2
DEFINITION
Calcium di(2,5-dihydroxybenzenesulfonate) monohydrate.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).
CHARACTERS
Appearance: White or almost white, hygroscopic powder.
Solubility: Very soluble in water, freely soluble in anhydrous ethanol, very slightly soluble in 2-propanol, practically insoluble in methylene chloride.
IDENTIFICATION
A. Ultraviolet and visible absorption spectrophotometry.
B. Mix 1 mL of ferric chloride solution, 1 mL of a freshly prepared 10 g/L solution of potassium ferricyanide & and 0.1 mL of nitric acid R. To this mixture add 5 mL of freshly prepared solution S (see Tests): a blue colour and a precipitate are immediately produced.
C. 2 mL of freshly prepared solution S gives reaction of calcium.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water ;and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S, when freshly prepared, is clear and colourless.
pH: 4.5 to 6.0 for solution S.
Related substances: To pass the test of Liquid chromatography
Iron: Maximum 10 ppm, determined on 10 mL of solution S.
Water: 4.0 per cent to 6.0 per cent, determined on 0.500 g.
We also supply Calcium Dobesilate Monohydrate EP Grade.
The Uses of Calcium Dobesilate Monohydrate:
Calcium Dobesilate is used in the treatment of piles, diabetic retinopathy, varicose veins and other things.
The MSDS-SDS Hazard Statement of Calcium Dobesilate Monohydrate:
Calcium Dobesilate Monohydrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 11-Nov-24
1. Product Identification
Product Name & Other Names: Calcium Dobesilate Monohydrate or 2,5-Dihydroxybenzenesulfonic acid calcium salt hydrate.
CAS Number: 20123-80-2
Relevant Uses: Industrial use only.
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Skin corrosion/irritation Category 2
Serious eye irritation/damage Category 2A
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3
Labeling according GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Word: Warning
Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Calcium Dobesilate Monohydrate or 2,5-Dihydroxybenzenesulfonic acid calcium salt hydrate.
CAS Number: 20123-80-2
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: May be combustible at high temperature.
Products of Combustion: Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Sulfur Oxides.
Fire: Slightly flammable on heating.
Explosion: Slightly explosive on heating.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill: Avoid touching the spilled material. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Specified.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Colorless white powder or crystals.
Odor: Faint to None.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting point/freezing point: No data found.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: It is soluble in water.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Sulfur Oxides.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles and heat.
11. Toxicological Information
Acute toxicity: Harmful if inhaled. Irritating to skin and eyes.
Toxicity data:
LD50: Oral: Rat: 7061 mg/Kg
LD50: Intravenous: Rat: 750 mg/Kg
LD50: Intraperitoneal: Mouse: 876 mg/Kg
Carcinogenic Effects: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Mutagenic Effects: No data found.
Teratogenic Effects: No data found.
Developmental Toxicity: No data found..
12. Ecological Information
Environmental Toxicity: No data found.
Mutagenic Effects: No data found.
Teratogenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control norms.
14. Transport Information
USA DOT & ADR/RID Classification: Not controlled.
Canada TDG Classification: Not controlled.
IATA: Not controlled.
15. Regulatory Information
USA:
California Prop. 65 Components: Not listed by the California to cause cancer, birth defects, or any other reproductive harm.
SARA 311/312: See section 2.
Section 16 - Additional Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Calcium Dobesilate Monohydrate Structure
CAS Number 20123-80-2, Calcium Dobesilate Monohydrate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 15-nov-24
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