CAS Number 7757-93-9, 65-85-0 and 7789-77-7, Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous USP NF BP Ph Eur FCC Food Grade Manufacturers Exporters
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CAS Number 7757-93-9, 65-85-0 and 7789-77-7, Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Manufacturer Exporter
For Properties Specifications of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Click Properties, Specifications of Dicalcium Phosphate or Calcium Phosphate Dibasic Dihydrate or Calcium Hydrogen Phosphate Anhydrous Manufacturer.
For Uses of Dicalcium Phosphate or Calcium Phosphate Dibasic Dihydrate Anhydrous or Calcium Hydrogen Phosphate Click Uses of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Manufacturer.
For For SDS MSDS Sheet of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Click SDS Safety Data Sheet MSDS Sheet of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Manufacturer.
The Properties and Specifications of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous:
Dibasic Calcium Phosphate USP NF Grade Specifications
Dibasic Calcium Phosphate
CaHPO4 136.06
Phosphoric acid, calcium salt (1:1).
Calcium phosphate (1:1) CAS 7757-93-9
Dihydrate 172.09 CAS 7789-77-7
Dibasic Calcium Phosphate is anhydrous or contains two molecules of water of hydration. It contains not less than 98.0 percent and not more than 105.0 percent of anhydrous dibasic calcium phosphate (CaHPO4) or of dibasic calcium phosphate dihydrate (CaHPO4·2H2O).
Labeling: Label it to indicate whether it is anhydrous or the dihydrate.
Identification:
A: Dissolve about 100 mg by warming with a mixture of 5 mL of 3 N hydrochloric acid and 5 mL of water, add 2.5 mL of 6 N ammonium hydroxide drop wise, with shaking, and then add 5 mL of ammonium oxalate TS: a white precipitate is formed.
B: To 10 mL of a warm solution (1 in 100) in a slight excess of nitric acid add 10 mL of ammonium molybdate TS: a yellow precipitate of ammonium phosphomolybdate is formed.
Loss on ignition: Ignite it at 800 to 825 to constant weight: anhydrous Dibasic Calcium Phosphate loses between 6.6% and 8.5% of its weight, and the dihydrate form of Dibasic Calcium Phosphate loses between 24.5% and 26.5% of its weight.
Carbonate: Mix 1.0 g with 5 mL of water, and add 2 mL of hydrochloric acid: no effervescence occurs.
Chloride: To 0.30 g add 10 mL of water and 2 mL of nitric acid, and warm gently, if necessary, until no more dissolves. Dilute to 25 mL, filter, if necessary, and add 1 mL of silver nitrate. TS: the turbidity does not exceed that produced by 1.0 mL of 0.020 N hydrochloric acid (0.25%).
Sulfate: Dissolve 1.0 g in the smallest possible amount of 3 N hydrochloric acid, dilute with water to 100 mL, and filter, if necessary. To 20 mL of the filtrate add 1 mL of barium chloride. TS: the turbidity does not exceed that produced by 1.0 mL of 0.020 N sulfuric acid (0.5%).
Arsenic:The limit is 3 µg per g.
Barium: Heat 0.50 g with 10 mL of water, and add hydrochloric acid drop wise, stirring after each addition, until no more dissolves. Filter, and to the filtrate add 2 mL of potassium sulfate TS: no turbidity is produced within 10 minutes.
Heavy metals: the limit is 0.003%.
Limit of acid-insoluble substances: not more than 0.2% of acid-insoluble substances is found.
Limit of fluoride: [NOTE—Prepare and store all solutions in plastic containers.]: the limit is 0.005%.
We also offer Directly Compressible Dicalcium Phosphate
Dibasic Calcium Phosphate BP Ph Eur Grade Specifications
Calcium Hydrogen Phosphate Dihydrate
CaHPO4,2H2O -- 172.1 -- CAS 7789-77-7
DEFINITION
Content: Dibasic Calcium Phosphate 98.0 per cent to 105.0 per cent.
CHARACTERS
Appearance: White, crystalline powder.
Solubility: Practically insoluble in cold water and in alcohol. It dissolves in dilute hydrochloric acid and in dilute nitric acid.
IDENTIFICATION
A. Dissolve 0.1 g in a mixture of 5 ml of dilute nitric acid and 5 ml of water. The solution gives reaction of phosphates.
B. 5 mg gives reaction of calcium.
C. It complies with the limits of the assay.
TESTS
Solution S: Dissolve 2.5 g in 20 ml of dilute hydrochloric acid, filter if necessary and add dilute ammonia until a precipitate is formed. Add just sufficient dilute hydrochloric acid to dissolve the precipitate and dilute to 50 ml with distilled water.
Carbonates: Shake 0.5 g with 5 ml of carbon dioxide-free water and add 1 ml of hydrochloric acid. No effervescence is produced.
Chlorides: Maximum 330 ppm.
Dissolve 0.5 g in a mixture of 1 ml of nitric acid and 10 ml of water and dilute to 50 ml with water. 15 ml of the solution complies with the limit test for chlorides.
Fluorides: Maximum 100 ppm.
Sulphates: Maximum 0.5 per cent.
Arsenic: Maximum 10 ppm.
Barium: To 10 ml of solution S add 0.5 ml of dilute sulphuric acid. After 15 min, any opalescence in the solution is not more intense than that in a mixture of 10 ml of solution S and 0.5 ml of distilled water.
Iron: Maximum 400 ppm.
Heavy metals: Maximum 40 ppm.
1 ml of 0.1 M sodium EDTA is equivalent to 17.21 mg of CaHPO4,2H2O.
We also offer Directly Compressible Dicalcium Phosphate
Calcium Phosphate, Dibasic FCC Food Grade Specifications
Dicalcium Phosphate
CaHPO4 Formula weight, anhydrous 136.06
CaHPO4·2H2O Formula weight, dihydrate 172.09
INS: 341(ii) CAS: anhydrous 7757-93-9
CAS: dihydrate 7789-77-7
DESCRIPTION
Calcium Phosphate, Dibasic, occurs as a white powder. It is anhydrous or contains two molecules of water of hydration. It is stable in air. It is insoluble in alcohol, is practically insoluble in water, but is readily soluble in dilute hydrochloric and nitric acids.
Function: Leavening agent; dough conditioner; nutrient; yeast food.
REQUIREMENTS
Labeling: Indicate whether it is anhydrous or the dihydrate.
Identification:
A. Dissolve about 100 mg of sample by warming it with a mixture of 5 mL of 2.7 N hydrochloric acid and 5 mL of water. Add 2.5 mL of 6 N ammonium hydroxide, drop-wise, with shaking, and then add 5 mL of ammonium oxalate TS. A white precipitate forms.
B. Add 10 mL of ammonium molybdate TS to 10 mL of a warm 1:100 aqueous solution in a slight excess of nitric acid. A yellow precipitate of ammonium phosphomolybdate forms.
Assay Anhydrous or Dihydrate: Not less than 97.0% and not more than 105.0% Dibasic Calcium Phosphate.
Arsenic: Not more than 3 mg/kg.
Fluoride: Not more than 0.005%.
Lead: Not more than 2 mg/kg.
Loss on Ignition Anhydrous: Between 7.0% and 8.5%; Dihydrate: Between 24.5% and 26.5%.
The Uses of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous:
Dibasic calcium phosphate is mainly used as a dietary supplement in prepared breakfast cereals, dog treats, enriched flour, and noodle products. It is also used as a tableting agent in some pharmaceutical preparations. It is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. Various calcium phosphates are used as diluents in the pharmaceutical industry.
The MSDS-SDS Hazard Statement of Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous:
Calcium Phosphate Dibasic SDS GHS, Safety Data Sheet
or Dicalcium Phosphate MSDS Sheet, Material Safety Data Sheet 09-Jan-23
1. Product Identification
Product Name & Other Names: Calcium Phosphate Dibasic or Dicalcium Phosphate or Calcium monohydrogen phosphate or Phosphoric acid, calcium salt (1:1) or Secondary Calcium Phosphate.
CAS No.: 7757-93-9
EINECS EC Number: 231-826-1
Molecular Weight: 136.06
Chemical Formula: CaHPO4
Relevant uses and uses advised against (if any): Laboratory and Industrial Manufacturing Use.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Words: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
3. Composition/Information on Ingredients
Product Name & Other Names: Calcium Phosphate Dibasic or Dicalcium Phosphate or Calcium monohydrogen phosphate or Phosphoric acid, calcium salt (1:1) or Secondary Calcium Phosphate.
CAS No.: 7757-93-9
EINECS EC Number: 231-826-1
4. First Aid Measures
Always seek medical advice after the first aid treatment.
Inhalation: If Dibasic Calcium Phosphate inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Not expected to require first aid measures. If large amounts were swallowed, give water to drink and get medical advice.
Skin Contact: Not expected to require first aid measures. Wash exposed area with soap and water. Get medical advice if irritation develops.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
5. Fire Fighting Measures
Fire: Not considered to be a fire hazard.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: Dibasic Calcium Phosphate is fine, white powder.
Odor: Odorless.
Odor threshold: Not available.
pH: Not available.
Relative density: around 2.3
Boiling Point: Decomposes.
Melting Point: Decomposes at red heat.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Practically insoluble in water.
Viscosity: Not available.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: No information found.
Hazardous Polymerization: Will not occur.
Incompatibilities: No incompatibility data found.
Conditions to Avoid: Excessive dust generation.
11. Toxicological Information
Oral rat LD50: 3986 mg/kg; Skin rabbit LD50: > 2 gm/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
12. Ecological Information
Environmental Toxicity: Not much found.
LC50 – Daphnia magna (Water flea) - >1,000 mg/l – 96 hours.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IMDG/IMO & IATA/ICAO: Not controlled.
15. Regulatory Information
USA:SARA 311/312: See section 2.
California Proposition 65: Not Listed.
DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Structure
CAS Number 7757-93-9, 65-85-0 and 7789-77-7, Dicalcium Phosphate or Calcium Phosphate Dibasic or Calcium Hydrogen Phosphate Dihydrate Anhydrous Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 9-jan-23
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