CAS Number 38304-91-5, Minoxidil USP BP Ph Eur EP IP Grade Manufacturers Exporters
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CAS Number 38304-91-5, Minoxidil USP BP Ph Eur EP IP Manufacturer Exporter
For Properties Specifications of Minoxidil Click Properties, Specifications of Minoxidil Manufacturer.
For Uses of Minoxidil Click Uses of Minoxidil Manufacturer.
For For SDS MSDS Sheet of Minoxidil Click SDS Safety Data Sheet MSDS Sheet of Minoxidil Manufacturer.
The Properties and Specifications of Minoxidil:
Minoxidil USP Grade Specifications:
C9H15N5O --- 209.25
2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide;
2,4-Diamino-6-piperidinopyrimidine 3-oxide CAS 38304-91-5
UNII: 5965120SH1
DEFINITION
Minoxidil contains NLT 97.0% and NMT 103.0% of minoxidil (C9H15N5O), calculated on the dried basis.
IDENTIFICATION
A. Infrared Absorption: Do not dry specimens.
Residue on Ignition: NMT 0.5%
Organic Impurities: NMT 1.5%
Loss on Drying: Dry a sample at 50C and at a pressure not exceeding 5 mm of mercury for 3 h. Acceptance criteria: NMT 0.5%
Minoxidil BP Ph Eur Grade Specifications:
C9H15N5O --- 209.3 CAS 38304-91-5
Action and use: Vasodilator; treatment of hypertension; male pattern baldness.
DEFINITION
6-(Piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide.
Content: 99.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Slightly soluble in water, soluble in methanol and in propylene glycol.
IDENTIFICATION
First identification: B
Second identification: A, C, D
A. Ultraviolet and visible absorption spectrophotometry.
B. Infrared absorption spectrophotometry.
C. Thin-layer chromatography.
D. Dissolve about 10 mg in 1 mL of methanol. Add 0.1 mL of copper sulfate solution. A green colour develops. The solution becomes greenish-yellow on the addition of 0.1 mL of dilute hydrochloric acid.
Related substances: To pass the test by Liquid chromatography.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
We also supply Minoxidil EP IP Grade.
The Uses of Minoxidil:
Minoxidil or 2,4-Diamino-6-piperidinopyrimidine 3-oxide is a medication used for the treatment of high blood pressure and pattern hair loss.
The MSDS-SDS Hazard Statement of Minoxidil:
Minoxidil SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 10-Nov-24
1. Product Identification
Product Name & Other Names: Minoxidil
CAS No.:38304-91-5
EINECS EC Number: 253-874-2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4, H302
Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements  Harmful Irritant |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Minoxidil
CAS No.:38304-91-5
EINECS EC Number: 253-874-2
4. First Aid Measures
Always get medical attention after the first aid is over.
Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.
5. Fire Fighting Measures
Fire: Not considered to be a fire hazard. May be combustible at high temperature.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture: Toxic fumes, Carbon oxides, Nitrogen oxides (NOx) and Cyanides.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Room temperature. Short term shipping may be ambient.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White to off-white crystalline powder.
Odor: Odorless.
Odor threshold: Not applicable.
pH: No data found.
Relative density: No data found.
Melting point: 248C.
Boiling point: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Slightly soluble in water. Soluble in methanol and in propylene glycol. Very slightly soluble in ether.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage. Forms explosive mixtures with air on intense heating. Fine distribution, when whirled up a dust explosion potential may generally be assumed.
Hazardous Decomposition Products: May produce toxic fumes, carbon oxides, nitrogen oxides (NOx) and cyanides when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flame, ignition sources, dusting, and incompatibles.
11. Toxicological Information
LD50 oral rat 1321 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Germ cell mutagenicity: Not available.
Reproductive toxicity: No data found.
Developmental Effects: No data found.
Teratogenicity: No data found.
12. Ecological Information
Toxicity: No data found.
Environmental Fate: No data found.
Persistence and degradability: No data found.
Mobility in soil: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control norms.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IATA: Not controlled.
IMDG/IMO: Not controlled.
15. Regulatory Information
USA:
SARA 311/312 Hazardous Categorization: Acute Health Hazard. See section 2.
California Proposition 65: This product does not contain any Proposition 65 chemicals.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Minoxidil Structure
CAS Number 38304-91-5, Minoxidil Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 11-dec-24
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