CAS Number 10191-41-0 & 1406-18-4, DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol USP BP Ph Eur Grade Manufacturers Exporters
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CAS Number 10191-41-0 & 1406-18-4, DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol USP BP Ph Eur Manufacturer Exporter
For Properties Specifications of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Click Properties, Specifications of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Manufacturer.
For Uses of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Click Uses of aaa Manufacturer.
For For SDS MSDS Sheet of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Click SDS Safety Data Sheet MSDS Sheet of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Manufacturer.
The Properties and Specifications of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol:
all-rac-Alpha-Tocopherol BP Ph Eur Grade:
C29H50O2 -- 430.7 -- 10191-41-0
Action and use: Used in prevention and treatment of vitamin E deficiencies.
DEFINITION
all-rac-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-ol.
Content: 96.0 per cent to 102.0 per cent.
CHARACTERS
Appearance: Clear, colourless or yellowish-brown, viscous, oily liquid.
Solubility: Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol, in methylene chloride and in fatty oils.
IDENTIFICATION
First identification: A, B
Second identification: A, C
A. Optical rotation: -0.01° to + 0.01°.
Dissolve 2.50 g in anhydrous ethanol and dilute to 25.0 mL with the same solvent.
B. Infrared absorption spectrophotometry. To pass the test.
C. Thin-layer chromatography. To pass the test.
TESTS
Related substances: To pass the test.
Assay: To pass the test.
Vitamin E USP Grade Specifications:
DEFINITION
Vitamin E is a form of alpha tocopherol (C29H50O2). It includes the following: d- or dl-alpha tocopherol (C29H50O2); d- or dl-alpha tocopheryl acetate (C31H52O3); d- or ;dl-alpha tocopheryl acid succinate (C33H54O5). It contains NLT 96.0% and NMT 102.0% of C29H50O2, C31H52O3, or C33H54O5, respectively.
IDENTIFICATION
A. To pass the test ----
B. Optical Rotation. To pass the test ----
ASSAY
To pass the test ----
Packaging and Storage: Preserve in tight containers, protected from light. Protect d- or dl-alpha tocopherol with a blanket of an inert gas.
All-rac-_-Tocopherol FCC Food Grade Specifications:
DL-_-Tocopherol --- C29H50O2, Formula Weight 430.71
INS: 307c, CAS: 10191-41-0
DESCRIPTION
All-rac-_-Tocopherol occurs as a yellow to amber, clear, viscous oil. It is a form of vitamin E. It oxidizes and darkens in air and on exposure to light. It is insoluble in water; freely soluble in alcohol; and miscible with acetone, with chloroform, with ether, with fats, and with vegetable oils.
Function: Nutrient; antioxidant.
REQUIREMENTS
Labeling: All label claims that are in terms of International Units (IU) should be based on the following: 1 mg of all-rac-α-Tocopherol = 1.1 IU.
Identification:
A. Dissolve about 10 mg of sample in 10 mL of absolute alcohol; add, with swirling, 2 mL of nitric acid; and heat at about 75° for 15 min. A bright red to orange color develops.
B. The retention time of the major peak (excluding the solvent peak) in the chromatogram of the Assay Preparation is the same as that of the Standard Preparation, both relative to the Internal Standard Solution, as obtained in the Assay.
C. If the isomeric form is not otherwise known, determine the optical rotation of a 1:10 solution in chloroform. The optical rotation is approximately±0.05°.
Assay: Not less than 96.0% and not more than 102.0% of C29H50O2.
Acidity: Passes test.
Lead: Not more than 2 mg/kg.
The Uses of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol:
DL α-Tocopherol is the main source found in supplements and in the European diet. It has vitamin E activity. α-Tocopherol is the form of vitamin E that is preferentially absorbed and accumulated in humans. Its IUPAC name is 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-ol. It is used in dietary supplements. DL-alpha-Tocopherol is used as an antioxidant to increase the stability of fats.
The MSDS-SDS Hazard Statement of DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol:
DL alpha-Tocopherol or DL α-Tocopherol
SDS, Safety Data Sheet
MSDS
1. Product Identification
Product Name & Other Names: DL alpha-Tocopherol or DL α-Tocopherol
CAS Number: 10191-41-0 & 1406-18-4
EINECS EC Number: 233-466-0
Molecular Formula: C29H50O2
Molecular Weight: 430.7
Relevant uses and uses advised against (if any): Industrial Manufacturing Use.
Supplier: As per letterhead above.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Sensitization, Skin Category 1, H317
Labelling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements Irritant |
Signal Words (GHS-USA): Warning
Hazard statements (GHS-USA):
H317: May cause an allergic skin reaction.
Precautionary statements (GHS-USA):
P233: Keep container tightly closed.
P260: Do not breathe mist, vapors, spray.
P264: Wash exposed skin thoroughly after handling.
P270: Do not eat, drink, or smoke when using this product.
P280: Wear protective clothing, protective gloves, eye protection, face protection.
P301+P330+P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P314: Get Medical advice/attention if you feel unwell.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P337+ P313 If eye irritation persists: Get medical advice/ attention.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi Irritant.
Risk Phrases:
R43 May cause sensitization by skin contact.
3. Composition/Information on Ingredients
Product Name & Other Names: DL alpha-Tocopherol or DL α-Tocopherol
CAS Number: 10191-41-0 & 1406-18-4
EINECS EC Number: 233-466-0
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: Not a fire hazard but it may ignite at higher temperature
Flash Points: 240C literature.
Products of Combustion: Carbon dioxide, Carbon monoxide, fumes.
Fire: Flammable in the presence of open flame.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Avoid dust-mist formation. Avoid breathing dust-mist. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Do not ingest. Do not breathe dust-mist. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment.
Avoid contact with skin and eyes. Avoid formation of dust-mist and aerosols. Wash hands thoroughly after handling. Provide appropriate exhaust ventilation at places where dust/mist is formed. If you feel unwell, seek medical attention.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Keep away from heat and flame. Air Sensitive. Light Sensitive. Storage at ambient temperatures.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Clear to yellow viscous oil. Liquid. It oxidizes and darkens in air and on exposure to light.
Odor: Nearly odorless.
Odor threshold: Not available.
pH: Not available.
Relative density: about 0.95
Melting point/freezing point: 2.5-3.5C literature.
Initial boiling point and boiling range: 200-220C literature.
Flash point: 240C literature.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Insoluble in water, freely soluble in ethanol, miscible in ether.
Viscosity: Not available.
Molecular Formula: C29H50O2
Molecular Weight: 430.7
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Carbon dioxide, Carbon monoxide & Fumes.
Hazardous Polymerization: Possible.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles, heat & light.
11. Toxicological Information
Toxicity data
Oral Rat LD50 > 4000 mg kg.
Dermal Rat LD50 > 3000 mg/kg
Carcinogenic Effects: Not know as carcinogen.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
12. Ecological Information
Toxicity to fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IATA/ICAO ADR/RID & IMDG/IMO: Not regulated.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H317: May cause an allergic skin reaction.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi Irritant.
Risk Phrases:
R43 May cause sensitization by skin contact.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals Industries Pvt. Ltd. is an off-shoot of Anmol Chemicals and Anmol Chemicals & Pharmaceuticals, Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals Industries Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Structure
CAS Number 10191-41-0 & 1406-18-4, DL alpha-Tocopherol or All-Rac-Aplha-Tocopherol Manufacturer Exporter
ANMOL CHEMICALS INDUSTRIES Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: 91-22-65290110
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 25-may-26
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