CAS Number 386750-22-7, Desvenlafaxine Succinate Monohydrate USP NF Grade Manufacturers Exporters
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CAS Number 386750-22-7, Desvenlafaxine Succinate or Desvenlafaxine Succinate Monohydrate USP NF Manufacturer Exporter
For Properties Specifications of Desvenlafaxine Succinate Click Properties, Specifications of Desvenlafaxine Succinate Manufacturer.
For Uses of Desvenlafaxine Succinate Click Uses of Desvenlafaxine Succinate Manufacturer.
For For SDS MSDS Sheet of Desvenlafaxine Succinate Click SDS Safety Data Sheet MSDS Sheet of Desvenlafaxine Succinate Manufacturer.
The Properties and Specifications of Desvenlafaxine Succinate:
Desvenlafaxine Succinate USP NF Grade Specifications:
C16H25NO2•C4H6O4•H2O --- 399.48
C16H25NO2•C4H6O4 --- 381.47
Butanedioic acid, compound with 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol (1:1), monohydrate;
1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol hydrogen butanedioate monohydrate CAS 386750-22-7
UNII: ZB22ENF0XR
Anhydrous CAS 448904-47-0
UNII: H9E1T0BI90.
DEFINITION
Desvenlafaxine Succinate contains NLT 98.0% and NMT 102.0% of desvenlafaxine succinate C16H25NO2•C4H6O4), calculated on the anhydrous basis.
IDENTIFICATION
A. SPECTROSCOPIC IDENTIFICATION TESTS, Infrared Spectroscopy.
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
Organic Impurities: To pass the test.
Water Determination: 4.0% to 5.2%
Packaging and Storage: Preserve in tight, light-resistant containers.
The Uses of Desvenlafaxine Succinate:
Desvenlafaxine Succinate is used as an antidepressant and for anxiety disorder.
The MSDS-SDS Hazard Statement of Desvenlafaxine Succinate:
Desvenlafaxine Succinate or Desvenlafaxine Succinate Monohydrate SDS Sheet, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 10-Nov-24
1. Product Identification
Product Name & Other Names: Desvenlafaxine Succinate or Desvenlafaxine Succinate Monohydrate.
CAS No.: 386750-22-7
EINECS EC Code: 692-113-2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Words: None
Hazards not otherwise classified (HNOC):
May cause mild skin irritation.
May cause mild eye irritation.
May cause mild respiratory irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a comfortable position for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Desvenlafaxine Succinate or Desvenlafaxine Succinate Monohydrate.
CAS No.: 386750-22-7
EINECS EC Code: 692-113-2
4. First Aid Measures
Always seek medical advice after the first aid treatment.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact the medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention.
Eye Contact: Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Combustible at high temperature. High heat or direct flame is necessary to cause ignition. Toxic fumes, carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: At high temperature, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Dry chemical, foam, water spray or carbon dioxide. Do not use a solid stream of water since the stream will scatter and spread the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place it in an appropriate waste disposal container.
Large Spill: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove it into an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep the container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cold, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material. Storage : Refrigerate. OK to freeze. Short-term shipping may be ambient.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White to Off-White Powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Melting point: 127C to 135C.
Boiling point: No data found.
Relative density: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Soluble in water and DMSO.
Viscosity: No data found.
Molecular Weight: 399.48
Chemical Formula: C16H25NO2•C4H6O4•H2O
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: Strong oxidizing agents, heat, and sparks.
Conditions to Avoid: Heat, flames, sunlight, ignition sources and incompatibles.
11. Toxicological Information
Oral Rat LD50: No data found.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: No data found.
Mutagenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.
12. Ecological Information
Toxicity to fish: No data found.
Mobility: Likely to be mobile due to water solubility.
Biodegradability: Expected to be biodegradable
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control norms.
14. Transport Information
DOT USA & ADR/RID Europe: Not controlled.
IMDG/IMO: Not controlled.
IATA/ICAO: Not controlled.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.
16. Other Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their judgment in determining its appropriateness for a particular purpose.
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Desvenlafaxine Succinate Monohydrate USP NF Structure
CAS Number 386750-22-7, Desvenlafaxine Succinate Monohydrate USP NF Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 18-nov-24
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