CAS Number 87-28-5, Glycol Salicylate or Hydroxyethyl Salicylate EP BP Ph Eur Grade Manufacturers Exporters
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CAS Number 87-28-5, Glycol Salicylate or Hydroxyethyl Salicylate EP BP Ph Eur Grade Manufacturer Exporter
For Properties Specifications of Glycol Salicylate or Hydroxyethyl Salicylate Click Properties, Specifications of Glycol Salicylate or Hydroxyethyl Salicylate Manufacturer.
For Uses of Glycol Salicylate or Hydroxyethyl Salicylate Click Uses of Glycol Salicylate or Hydroxyethyl Salicylate Manufacturer.
For For SDS MSDS Sheet of Glycol Salicylate or Hydroxyethyl Salicylate Click SDS Safety Data Sheet MSDS Sheet of Glycol Salicylate or Hydroxyethyl Salicylate Manufacturer.
The Properties and Specifications of Glycol Salicylate or Hydroxyethyl Salicylate:
Hydroxyethyl Salicylate BP Ph Eur Grade Specifications:
C9H10O4 --- 182.2 CAS 87-28-5
DEFINITION
2-Hydroxyethyl 2-hydroxybenzoate.
Content: 98.0 per cent to 102.0 per cent.
CHARACTERS
Appearance: Oily, colourless or almost colourless liquid, or colourless crystals.
Solubility: Sparingly soluble in water, very soluble in acetone and in methylene chloride, freely soluble in ethanol (96 per cent).
Melting point: About 21C.
IDENTIFICATION
First identification: A, B
Second identification: A, C, D, E
A. Refractive index.
B. Infrared absorption spectrophotometry.
C. Examine the chromatograms ---.
D. To 1 mL of solution S (see Tests), add 1 mL of water and 0.2 mL of ferric chloride solution R2. A violet-red colour appears which disappears immediately after the addition of 2 mL of dilute acetic acid. A very faint violet colour may remain.
E. In a test tube 160 mm long, mix 1.0 g with 2.0 g of finely powdered manganese sulfate. Insert 2 cm into the test-tube a strip of filter paper impregnated with a freshly prepared mixture of 1 volume of a 20 per cent V/V solution of diethanolamine and 11 volumes of a 50 g/L solution of sodium nitroprusside adjusted to pH 9.8 with 1 M hydrochloric acid. Heat the test-tube over a naked flame for 1-2 min. The filter paper becomes blue.
TESTS
Solution S: Dissolve 2.5 g in 40 mL of ethanol (96 per cent) and dilute to 50 mL with distilled water.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 2 mL of solution S add 0.1 mL of methyl red solution and 0.2 mL of 0.01 M sodium hydroxide. The solution is yellow. Add 0.3 mL of 0.01 M hydrochloric acid. The solution is red.
Relative density: 1.252 to 1.257.
Refractive index: 1.548 to 1.551.
Related substances: To pass the test by thin-layer chromatography.
Chlorides: Maximum 100 ppm.
Sulfates: Maximum 250 ppm.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Storage: Protected from light.
Glycol Salicylate or 2-Hydroxyethyl Salicylate or Ethylene Glycol Monosalicylate is also manufactured as in the latest EP Grade monograph.
The Uses of Glycol Salicylate or Hydroxyethyl Salicylate:
2-Hydroxyethyl Salicylate or Ethylene Glycol Monosalicylate is used in many topical creams and sprays for the relief of aches, pains, and stiffness of the muscles, joints, and tendons.
The MSDS-SDS Hazard Statement of Glycol Salicylate or Hydroxyethyl Salicylate:
Glycol Salicylate or 2-Hydroxyethyl Salicylate or Ethylene Glycol Monosalicylate SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 10-Dec 24
1. Product Identification
Product Name/Synonyms: Glycol Salicylate or 2-Hydroxyethyl Salicylate or Ethylene Glycol Monosalicylate.
CAS No.: 87-28-5
EINECS EC Number: 201-737-2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to authorized agents only.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
3. Composition/Information on Ingredients
Product Name/Synonyms: Glycol Salicylate or 2-Hydroxyethyl Salicylate or Ethylene Glycol Monosalicylate.
CAS No.: 87-28-5
EINECS EC Number: 201-737-2
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen and get medical attention immediately.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing and shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. Avoid solid water jet as it can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill: Harmful solid. Stop leaking without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce vapors.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store it with incompatible materials like strong oxidizers.Avoid dust formation and control ignition sources. Employ grounding, venting and explosion relief provisions in accord with accepted engineering practices in any process capable of generating dust and/or static electricity. Empty only into inert or non-flammable atmosphere. Storage: Pure @ -20C protected from light.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance: Viscous liquid or semi-solid..
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: about 1.25
Boiling Point: 294C literature.
Melting Point: 21C literature.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Slightly soluble in water.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizers.
Conditions to Avoid: Heat, dusting, and incompatibles.
11. Toxicological Information
Oral mouse LD50: 1380 mg/Kg.
Carcinogenicity: Not identified as probable or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
12. Ecological Information
Toxicity to fish: LC50 - Danio rerio (zebra fish) - 100 mg/l - 96 h.
Environmental Fate: This material is expected to readily biodegrade.
PBT and vPvB assessment: No data found.
Mobility: Will likely be mobile in the environment due to its water solubility.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules.
14. Transport Information
DOT (USA) & ADR/RID: Not regulated.
IMDG & IATA: Not regulated.
15. Regulatory Information
USA:
SARA 311/312: See section 2.
California Prop. 65 Components: Not listed for cancer or reproductive harm.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Glycol Salicylate or Hydroxyethyl Salicylate Structure
CAS Number 87-28-5, Glycol Salicylate or Hydroxyethyl Salicylate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 10-dec-24
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