CAS Number 13739-02-1, Diacerein or Diacetylrhein BP Ph Eur EP Food Grade Manufacturers Exporters
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CAS Number 13739-02-1, Diacerein or Diacetylrhein BP Ph Eur EP Manufacturer Exporter
For Properties Specifications of Diacerein or Diacetylrhein BP Ph Eur EP Click Properties, Specifications of Diacerein or Diacetylrhein Manufacturer.
For Uses of Diacerein or Diacetylrhein BP Ph Eur EP Click Uses of Diacerein or Diacetylrhein Manufacturer.
For For SDS MSDS Sheet of Diacerein or Diacetylrhein BP Ph Eur EP Click SDS Safety Data Sheet MSDS Sheet of Diacerein or Diacetylrhein Manufacturer.
The Properties and Specifications of Diacerein or Diacetylrhein BP Ph Eur EP:
Diacerein BP Ph Eur Grade Specifications:
C19H12O8 --- 368.3 CAS 13739-02-1
Action and use: Anti-inflammatory used in the treatment of arthritis and osteoarthritis.
Content: 98.0 per cent to 102.0 per cent (dried substance).
CHARACTERS
Appearance: Yellow, crystalline powder.
Solubility: Practically insoluble in water, soluble in dimethylacetamide, slightly soluble in tetrahydrofuran, practically insoluble in anhydrous ethanol.
IDENTIFICATION
Infrared absorption spectrophotometry.
TESTS
Impurities B and H: To pass the test by Liquid chromatography.
Related substances: To pass the test by Liquid chromatography.
Chromium: Maximum 10 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Storage: In an airtight container, protected from light.
The Uses of Diacerein or Diacetylrhein BP Ph Eur EP:
Diacerein or Diacetylrhein is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints).The MSDS-SDS Hazard Statement of Diacerein or Diacetylrhein BP Ph Eur EP:
Diacerein or Diacetylrhein SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 02-Nov-24
1. Product Identification
Product Name & Other Names: Diacerein or Diacetylrhein.
CAS No.: 13739-02-1
EINECS EC Number: 237-310-2
Molecular Formula: C19H12O8
Molecular Weight: 368.30
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Skin irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity - single exposure, Target Organs - Respiratory system. Category 3, H335
Labeling Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements  Irritant |
Signal Words: Warning
Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P264: Wash --- thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P362: Take off contaminated clothing and wash before reuse.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
Risk Phrase:
R36/37/38 = Irritating to eyes, respiratory system, and skin.
3. Composition/Information on Ingredients
Product Name & Other Names: Diacerein or Diacetylrhein.
CAS No.: 13739-02-1
EINECS EC Number: 237-310-2
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen and get medical attention immediately.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing and shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill:Corrosive solid. Contain spilled material. Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce vapor. Prevent entry into sewers, basements, or confined areas; dike if needed. Eliminate all ignition sources.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store it with incompatible materials like strong oxidizers. Storage: Room temperature. Recommended in a sealed container, cool and dark place, <15C.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: No information found.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g., lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Light yellow to Dark green powder to crystal.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: about 1.5 predicted.
Boiling Point: Not available.
Melting Point: 217C-218C literature.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor Density (Air=1): Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Negligible solubility in water.
Viscosity: Not available.
Molecular Formula: C19H12O8
Molecular Weight: 368.30
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizers
Conditions to Avoid: Heat, dusting, and incompatibles.
11. Toxicological Information
Oral rat LD50: Not available.
Carcinogenicity: This product is not classifiable as to its carcinogenicity based on its IARC, ACGIH, NTP, or EPA classification.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
Toxicity to fish: Not available.
Environmental Fate: Sufficient information is not available.
Environmental Toxicity: No information found.
Persistence and degradability: No data available.
Mobility in soil: No data available.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused Phthalic Acid in accordance with legal requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
IMDG & IATA: Not Regulated.
15. Regulatory Information
USA:
SARA 311/312 Hazards: Acute Health Hazard.
California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
Risk Phrase:
R36/37/38 = Irritating to eyes, respiratory system, and skin.
Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Diacerein or Diacetylrhein BP Ph Eur EP Structure
CAS Number 13739-02-1, Diacerein or Diacetylrhein BP Ph Eur EP Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 11-dec-24
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