CAS Number 112945-52-5 or 7631-86-9, Fumed Silica or Colloidal Silicon Dioxide or Hydrophobic Colloidal Anhydrous Silica EP USP NF BP Ph Eur FCC Food Grade Manufacturers Exporters
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CAS Number 112945-52-5 or 7631-86-9, Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide EP USP NF BP Ph Eur FCC Food GradeManufacturer Exporter
For Properties Specifications of Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide Click Properties, Specifications of aaa Manufacturer.
For Uses of Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide Click Uses of Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide Manufacturer.
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The Properties and Specifications of Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide:
Specifications of Colloidal Silicon Dioxide USP NF Grade:
SiO2 --- 60.08
Silica CAS 7631-86-9
Colloidal Silicon Dioxide is a submicroscopic fumed silica prepared by the vapor-phase hydrolysis of a silicon compound. When ignited at 1000 for 2 hours, it contains not less than 99.0 percent and not more than 100.5 percent of SiO2.
Identification:
A: Transfer about 5 mg to a platinum crucible and mix with about 200 mg of anhydrous potassium carbonate. Ignite at a red heat over a burner for about 10 minutes, and cool. Dissolve the melt in 2 mL of freshly distilled water, warming if necessary, and slowly add 2 mL of ammonium molybdate to the solution: a deep yellow color is produced.
B: [Caution: Avoid contact with o-tolidine when performing this test, and conduct the test in a wellventilated hood.] Place 1 drop of the yellow silicomolybdate solution obtained in Identification test A on a filter paper and evaporate the solvent. Add 1 drop of a saturated solution of o-tolidine in glacial acetic acid to reduce the silicomolybdate to molybdenum blue, and place the paper over ammonium hydroxide: a greenish blue spot is produced.
pH: between 3.5 and 5.5, in a 1 in 25 dispersion.
Loss on drying: Dry it in a tared platinum crucible at 105 for 2 hours: it loses not more than 2.5% of its weight. Retain the dried specimen, in the crucible, for the test for Loss on ignition.
Loss on ignition: Ignite the portion of Colloidal Silicon Dioxide, retained from the test for Loss on drying, at 1000C ± 25C to constant weight: the previously dried Colloidal Silicon Dioxide loses not more than 2.0% of its weight.
Arsenic: To pass the test. The limit is 8 microg per g.
Specifications of Hydrophobic Colloidal Anhydrous Silica BP Ph Eur Grade:
DEFINITION
Colloidal silicon dioxide partly alkylated for hydrophobation.
Content: 99.0 per cent to 101.0 per cent SiO2 (ignited substance).
CHARACTERS
Appearance: White or almost white, light, fine, amorphous powder, not wet-able by water.
Solubility: Practically insoluble in water and mineral acids except hydrofluoric acid. It dissolves slowly in hot solutions of alkali hydroxides.
IDENTIFICATION
A. About 25 mg ignited in a platinum crucible at 900 ± 50C for 2 h gives the reaction of silicates.
B. Water-dispersible fraction (see Tests).
TESTS
Chlorides: Maximum 250 ppm.
To 1.0 g add 30 mL of methanol and 20 mL of dilute nitric acid. Heat on a water-bath for 15 min stirring frequently. Cool, dilute to 50 mL with water and filter. Dilute 10 mL of the filtrate to 15 mL with water.
Water-dispersible fraction: Maximum 3.0 per cent.
Place 0.400 g in a 500 mL separating funnel, add 100 mL of water and shake for 1 min. Allow to stand for 1 h. Allow 90 mL of the aqueous phase to run out dropwise without filtration into a suitable dish dried at 140C and cooled in a desiccator. Evaporate to dryness at 140C, starting at a low temperature to avoid splashing. Cool in a desiccator. The residue weighs a maximum of 12 mg.
Loss on ignition: Maximum 6.0 per cent, determined on 0.200 g by ignition in a platinum crucible at 900 ± 50C for 2 h. It is advisable to place the crucible in a cold oven and then to heat up the oven. Allow to cool in a desiccator before weighing.
Specifications of Colloidal Anhydrous Silica BP Ph Eur Grade:
SiO2 --- 60.1 --- 7631-86-9
Action and use: Excipient.
DEFINITION
Content: 99.0 per cent to 100.5 per cent of SiO2 (ignited substance).
CHARACTERS
Appearance: White or almost white, light, fine, amorphous powder, with a particle size of about 15 ;nm.
Solubility: Practically insoluble in water and in mineral acids except hydrofluoric acid. It dissolves in hot solutions of alkali hydroxides.
IDENTIFICATION
About 20 mg gives the reaction of silicates.
TESTS
pH: 3.5 to 5.5.
Chlorides: Maximum 250 ppm.
To 1.0 g add a mixture of 20 mL of dilute nitric acid and 30 mL of water and heat on a water-bath for 15 min, shaking frequently. Dilute to 50 mL with water if necessary, filter and cool. Dilute 10 mL of the filtrate to 15 mL with water.
Loss on ignition: Maximum 5.0 per cent, determined on 0.200 g by ignition in a platinum crucible at 900 ± 50C for 2 h. Allow to cool in a desiccator before weighing.
Specifications of Colloidal Hydrated Silica BP Ph Eur Grade:
CAS 63231-67-4
Action and use: Excipient.
DEFINITION
Colloidal hydrated silica produced by precipitation or gelation process.
Content: 98.0 per cent to 100.5 per cent of SiO2 (ignited substance).
CHARACTERS
Appearance: White or almost white, light, fine, amorphous powder.
Solubility: Practically insoluble in water and in mineral acids, with the exception of hydrofluoric acid. It dissolves in hot solutions of alkali hydroxides.
IDENTIFICATION
About 20 mg gives the reaction of silicates.
TESTS
Solution S: To 2.5 g add 50 mL of hydrochloric acid and mix. Heat on a water-bath for 30 min, stirring from time to time. Maintain the original volume by adding dilute hydrochloric acid. Evaporate to dryness. Add to the residue a mixture of 8 mL of dilute hydrochloric acid and 24 mL of water. Heat to boiling and filter under reduced pressure through a sintered-glass filter (16). Wash the residue on the filter with a hot mixture of 3 mL of dilute hydrochloric acid and 9 mL of water. Wash with small quantities of water, combine the filtrate and washings and dilute to 50 mL with water.
pH: 4.0 to 7.0.
Suspend 1.0 g in 30 mL of a 75 g/L solution of potassium chloride.
Water-absorption capacity: In a mortar, triturate 5 g with 5 mL of water, added drop by drop. The mixture remains powdery.
Substances soluble in hydrochloric acid: Maximum 2.0 per cent.
In a platinum dish, evaporate to dryness 10.0 mL of solution S and dry to constant mass at 100-105C. The mass of the residue is not more than 10 mg.
Chlorides: Maximum 0.1 per cent.
Sulfates: Maximum 1 per cent.
Iron: Maximum 300 ppm.
Loss on ignition: Maximum 20.0 per cent, determined on 0.200 g in a platinum crucible by heating at 100-105C for 1 ;h and then at 900 ± 50C for 2 h.
We also offer Silica Colloidal Anhydrous EP Grade.
Specifications of Silicon Dioxide FCC Food Grade:
Synthetic Amorphous Silica
SiO2 Formula weight 60.08
INS: 551 CAS: 7631-86-9
DESCRIPTION
Silicon Dioxide occurs as an amorphous substance that shows a noncrystalline pattern when examined by X-ray diffraction. It is produced synthetically, either by a vapor-phase hydrolysisprocess, yielding fumed silica, or by a wet process, yielding precipitated silica, silica gel, colloidal silica, or hydrous silica. Fumed silica is produced in an essentially anhydrous state, whereas the wet-process products are obtained as hydrates or contain surface-adsorbed water.
Fumed silica occurs as a white, fluffy, nongritty powder of extremely fine particle size and is hygroscopic. The wet process silicas occur as white, fluffy powders or as white, microcellular beads or granules and are hygroscopic or absorb moisture from the air in varying amounts. All these forms of Silicon Dioxide are insoluble in water and in organic solvents but they are soluble in hydrofluoric acid and in hot, concentrated solutions of alkalies.
Function: Anticaking agent; defoaming agent; carrier; conditioning agent; chillproofing agent in malt beverages; filter aid.
REQUIREMENTS
Identification:
A. Place about 5 mg of sample into a platinum crucible, mix with 200 mg of anhydrous potassium carbonate and ignite over a burner at a red heat for about 10 min. Cool, dissolve the melt in 2 mL of freshly distilled water, warming if necessary, and slowly add 2 mL of ammonium molybdate. A deep yellow color appears.
B. Place 1 drop of the solution from Identification Test A on a filter paper and evaporate the solvent. Add 1 drop of a saturated solution of o-toluidine in glacial acetic acid and place the paper over ammonium hydroxide. A green-blue spot develops.
Assay: Fumed Silica: Not less than 99.0% of SiO2 after ignition; Precipitated Silica, Silica Gel, and Hydrous Silica: Not less than 94.0% of SiO2 after ignition.
Lead: Not more than 5 mg/kg.
Loss on Drying: Fumed Silica: Not more than 2.5%; Precipitated Silica and Silica Gel: Not more than 7.0%; Hydrous Silica: Not more than 70.0%; Colloidal Silica: Not more than 85.0%.
Loss on Ignition: Fumed Silica: Not more than 2.0% after drying; Silica Gel, Hydrous Silica, and Precipitated Silica: Not more than 8.5% after drying.
Soluble Ionizable Salts (as Na2SO4): Precipitated Silica, Silica Gel, and Hydrous Silica: Not more than 5.0%.
The Uses of Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide:
In the pharmaceutical industry, colloidal silicon dioxide is used in tablet-making, including use as an anti-caking agent, adsorbent, disintegrant, or glidant to allow powder to flow freely when tablets are processed.
The MSDS-SDS Hazard Statement of Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide:
Fumed Silica or Colloidal Silicon Dioxide SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 10-Dec-24
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Fumed Silica or Colloidal Silicon Dioxide.
CAS Number: 112945-52-5 or 7631-86-9.
EINECS EC Code: 231-545-4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according GHS & Regulation (EC) No 1272/2008
GHS Label Elements |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Fumed Silica or Colloidal Silicon Dioxide.
CAS Number: 112945-52-5 or 7631-86-9.
EINECS EC Code: 231-545-4
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Products of Combustion: No information available.
Fire Fighting Media and Instructions: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Section 6: Accidental Release Measures
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill: Contain spilled material. Do not inhale vapors, dust, mist or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials.
Section 8: Exposure Controls/Personal Protection
Exposure Limits: US OSHA PEL: 6 mg/m3
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels low.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent Gloves.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product.
Section 9: Physical and Chemical Properties
Physical state and appearance: White powder.
Odor: Odorless.
Odor threshold: Not applicable.
pH: No data found.
Specific Gravity: No data found.
Melting point/freezing point: No data found.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: No data found.
Viscosity: No data found.
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions to avoid: Incompatible materials, strong oxidizing agents, strong acids, strong bases.
Incompatibility with various substances: Chlorine trifluoride, hydrogen fluoride, oxygen difluoride.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals: Oral LD50: LD50/oral/rat = > 5000 mg/kg. LD50/dermal/rabbit = > 2000 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive Effects: No data found.
Developmental Effects: No data found.
Section 12: Ecological Information
Toxicity to fish: Fish (Brachydanio rerio) ECO (96 hours): > 10,000 mg/l.
Persistence and Degradability: No data found.
Mobility: No data found.
Bioaccumulation/ Accumulation: No data found.
Results of PBT and vPvB assessment: No data found for assessment.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations. Follow all the pollution control rules.
Section 14: Transport Information
DOT (USA) & ADR/RID: Not regulated.
IMDG & IATA: Not regulated.
Section 15: Other Regulatory Information
USA Federal and State Regulations:
California Prop. 65 Components: Not listed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide Structure
CAS Number 112945-52-5 or 7631-86-9, Hydrophobic Colloidal Anhydrous Silica or Fumed Silica or Colloidal Silicon Dioxide Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 11-dec-24
We manufacture:
Aluminium Sodium Silicate or Sodium Aluminosilicate