CAS Number 2413-38-9, Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl BP Ph Eur EP Grade Manufacturers Exporters
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CAS Number 2413-38-9, Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Manufacturer Exporter
For Properties Specifications of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Click Properties, Specifications of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Manufacturer.
For Uses of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Click Uses of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Manufacturer.
For For SDS MSDS Sheet of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Click SDS Safety Data Sheet MSDS Sheet of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Manufacturer.
The Properties and Specifications of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl:
Flupentixol Hydrochloride BP Ph Eur Grade Specifications:
C23H27Cl2F3N2OS --- 507.4 CAS 2413-38-9
Action and use: Dopamine receptor antagonist; neuroleptic.
Preparation: Flupentixol Tablets.
DEFINITION
2-[4-[3-[(EZ)-2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol dihydrochloride.
Content:
— flupentixol dihydrochloride: 98.0 per cent to 101.5 per cent (dried substance);
— (Z)-isomer: 42.0 per cent to 52.0 per cent.
CHARACTERS
Appearance: White or almost white powder.
Solubility: Very soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
IDENTIFICATION
First identification: A, D
Second identification: B, C, D
A. Infrared absorption spectrophotometry.
B. Thin-layer chromatography.
C. To pass the test.
D. It gives reaction of chlorides.
TESTS
Appearance of solution: The solution is clear and not more intensely coloured than reference solution. Dissolve 2.0 g of the substance to be examined in water and dilute to 20 mL with the same solvent.
pH: 2.0 to 3.0. Dissolve 0.5 g in carbon dioxide-free water and dilute to 50 mL with the same solvent.
Related substances: To pass the test by Thin-layer chromatography.
Impurity F: To pass the test by Liquid chromatography.
Loss on drying: Maximum 2.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g in a platinum crucible.
Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl EP Grade is also offered.
The Uses of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl:
Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl is a typical antipsychotic drug of the thioxanthene class used to treat schizophrenia and other psychoses. It acts as a potent dopamine D1 and D2 receptor antagonist.The MSDS-SDS Hazard Statement of Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl:
Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl SDS, Safety Data Sheet
MSDS
1. Product Identification
Product Name/Synonyms:Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl.
CAS No.:2413-38-9
EINECS EC Number: 219-321-4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements Irritant |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P501: Dispose of contents/container to authorized agents only.
3. Composition/Information on Ingredients
Product Name/Synonyms: Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl.
CAS No.: 2413-38-9
EINECS EC Number: 219-321-4
4. First Aid Measures
Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reusing. Thoroughly clean shoes before reusing them. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.
Notes to Physician: Treat symptomatically.
5. Fire Fighting Measures
Fire: It is not considered to be a fire hazard. However, it will burn at high temperature.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemicals, or carbon dioxide. Use water spray to cool fire-exposed containers.
Special hazards arising from the substance or mixture: Carbon oxides, Sulphur oxides, Chlorine & Fluorine compounds and Fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Use personal protective equipment. Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment, cleanup procedures and Storage: Contain spilled material. Pick up spills and place them in a suitable container for reclamation or disposal, using a method that does not generate dust.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wear personal protective equipment. Avoid ingestion and inhalation. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Avoid dust formation and control ignition sources. Storage: Protected from light. Preferably refrigerate. Short-term shipping may be ambient.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established by regulating bodies.
Ventilation System: In general, dilution ventilation is a satisfactory health hazard control for this substance. However, if conditions of use create discomfort for the worker, a local exhaust system should be considered.
Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance: White or almost white powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Boiling Point: No data found.
Melting Point: 233C to 234C literature.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Very soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: May produce oxides of sulfur, carbon, chlorine & fluorine compounds along with fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flame, ignition sources, dusting, and incompatibles.
11. Toxicological Information
Toxicity Data: LD50 Oral - Mouse - 423 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: No data found.
Reproductive Effects: No data found.
Developmental Effects: No data found.
12. Ecological Information
Environmental Fate: No data found.
Persistence and degradability: Unlikely to persist due to water solubility.
Toxicity: No data found.
Bioaccumulative potential: No data found.
Mobility in soil: Likely to be mobile due to water solubility.
PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. Dispose of containers and unused material in accordance with legal requirements.
14. Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
Sea Transport IMDG/IMO: Not controlled.
Air Transport IATA/ICAO: Not controlled.
15. Regulatory Information
USA:
SARA 311/312 Hazardous Categorization: See section 2.
California Proposition 65: This product does not contain any Proposition 65 chemicals.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals Industries Pvt. Ltd. is an off-shoot of Anmol Chemicals and Anmol Chemicals & Pharmaceuticals, Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals Industries Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Structure
CAS Number 2413-38-9, Flupentixol Dihydrochloride or Flupentixol Hydrochloride or Flupentixol HCl Manufacturer Exporter
ANMOL CHEMICALS INDUSTRIES Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: 91-22-65290110
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 23-may-26
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