CAS Number 152520-56-4, Nebivolol Hydrochloride IP EP Grade Manufacturers Exporters
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CAS Number 152520-56-4, Nebivolol Hydrochloride or Nebivolol HCl IP EP Manufacturer Exporter
For Properties Specifications of Nebivolol Hydrochloride or Nebivolol HCl Click Properties, Specifications of Nebivolol Hydrochloride or Nebivolol HCl Manufacturer.
For Uses of Nebivolol Hydrochloride or Nebivolol HCl Click Uses of Nebivolol Hydrochloride or Nebivolol HCl Manufacturer.
For For SDS MSDS Sheet of Nebivolol Hydrochloride or Nebivolol HCl Click SDS Safety Data Sheet MSDS Sheet of Nebivolol Hydrochloride or Nebivolol HCl Manufacturer.
The Properties and Specifications of Nebivolol Hydrochloride or Nebivolol HCl:
General Properties and Specifications of Nebivolol Hydrochloride or Narbivolol, or Nebilet:
Appearance: White to off-white powder.
Assay: Between 98% and 102%
Identifications: By comparison with standard. IR and HPLC.
Solubility: Soluble in water. Sparingly soluble in Dimethylformamide and slightly soluble in Methanol.
Related substance impurity: Single impurity >0.5% and total impurity >1%
Heavy metals: >20 ppm.
Sulfated ash: >0.2%
Residual solvent:
Methanol: >3000 ppm.
Acetonitrile: >410 ppm.
Isopropyl alcohol: >5000 ppm.
Diisopropyl ether: >1000 ppm.
Water by KF: >1%
Melting point: 219C to 222C.
Storage: 2C to 8C Refrigerate. OK to freeze. Shipping may be at room temperature. Protect from light.
We supply Nebivolol Hydrochloride or Narbivolol IP EP Grade.
The Uses of Nebivolol Hydrochloride or Nebivolol HCl:
Nebivolol is used to treat high blood pressure (hypertension). Nebivolol is a beta-blocker.
The MSDS-SDS Hazard Statement of Nebivolol Hydrochloride or Nebivolol HCl:
Nebivolol Hydrochloride or Narbivolol, or Nebilet SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 11-Nov-24
1. Product Identification
Product Name & Other Names: Nebivolol Hydrochloride or Narbivolol, or Nebilet.
CAS No.: 152520-56-4 (also 169293-50-9)
EINECS EC Code: 690-990-6
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: AS per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements None |
Signal Words: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product Name & Other Names: Nebivolol Hydrochloride or Narbivolol, or Nebilet.
CAS No.: 152520-56-4 (also 169293-50-9)
EINECS EC Code: 690-990-6
4. FIRST AID MEASURES
Always get medical attention after the first aid is over.
Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If swallowed, if conscious, give plenty of water. Immediately call a physician.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep a person warm, quiet, and get medical attention.
5. FIREFIGHTING PROCEDURES
Extinguisher Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet as it can spread fire.
Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.
Unusual Fire and Explosion Hazards: Heated to decomposition, however, toxic oxides of sulfur, chlorine compounds, oxides of nitrogen and oxides of carbon along with fumes may be evolved.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. SPILL OR LEAK PROCEDURES
Personal precautions, protective equipment, and emergency procedures: Ventilate area of spill. Avoid creating dust. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. SPECIAL PRECAUTIONS
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Provide appropriate exhaust ventilation at places where dust is formed. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like Strong oxidizing agents, Strong bases. Storage: 2C to 8C Refrigerate. Protect from light.
8. SPECIAL PROTECTION INFORMATION
Exposure limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. PHYSICAL DATA
Physical State: White to off-white powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting Point: 219C to 222C.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility in Water: No data found.
Viscosity: No data found.
10. REACTIVITY DATA
Stability: Stable.
Conditions to Avoid: Dust generation, Incompatibles
Incompatibility (Materials to Avoid): Strong oxidizing agents, Strong bases.
Hazardous Decomposition Products: Compounds of fluorine, chlorine compounds, nitrogen, and carbon oxides along with fumes.
Hazardous Polymerization: Will not occur.
11. TOXICITY DATA
Toxicity Data: No data found.
Carcinogenicity: Not listed as carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.
12. ECOLOGICAL DATA
Toxicity to fish, daphnia, and other aquatic invertebrates: No data found.
Persistence and Degradability: No data found.
Mobility: No data found.
Results of PBT and vPvB assessment: No data available for assessment.
13. DISPOSAL INFORMATION
Waste Disposal Methods: Dispose in accordance with all applicable regulations. Follow all the pollution control laws.
14. TRANSPORT INFORMATION
DOT (USA) & ADT/RID Europe: Not controlled.
IMDG & IATA: Not controlled.
15. REGULATORY INFORMATION
USA Regulations:
SARA 311/312 Hazard Categories: See section 2.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Nebivolol Hydrochloride or Nebivolol HCl Structure
CAS Number 152520-56-4, Nebivolol Hydrochloride or Nebivolol HCl Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 11-dec-24
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