CAS Number 10102-17-7 Pentahydrate and 7772-98-7 Anhydrous, Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous USP NF BP Ph Eur Analytical Reagent FCC Food Grade Manufacturers Exporters
------ 
CAS Number 10102-17-7 Pentahydrate and 7772-98-7 Anhydrous, Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Manufacturer Exporter
For Properties Specifications of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Click Properties, Specifications of aSodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrousaa Manufacturer.
For Uses of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Click Uses of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Manufacturer.
For For SDS MSDS Sheet of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Click SDS Safety Data Sheet MSDS Sheet of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Manufacturer.
The Properties and Specifications of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous:
Sodium Thiosulfate USP Grade Specifications
Na2S2O3-5H2O -- 248.19
Sodium Thiosulfate USP
Contains not less than 99.0 percent and not more than 100.5 percent of Na2S2O3, calculated on the anhydrous basis.
Identification:
A: To a solution (1 in 10) add a few drops of iodine TS: the color is discharged.
B: A solution (1 in 10) responds to the tests for Sodium and for Thiosulfate.
Water: Dry about 1.0 g, accurately weighed, in vacuum at 40 o to 45o for 16 hours: it loses between 32.0% and 37.0% of its weight.
Calcium: Dissolve 1 g Sodium Thiosulfate in 20 mL of water, and add a few mL of ammonium oxalate TS: no turbidity is produced.
Heavy metals: the limit is 0.002%.
Sodium Thiosulphate BP Ph Eur Grade Specifications
Na2S2O3-5H2O
Sodium Thiosulphate BP
DEFINITION
Content: 99.0 per cent to 101.0 per cent of Na2S2O3-5H2O.
CHARACTERS
Appearance: Transparent, colorless crystals, efflorescent in dry air.
Solubility: Very soluble in water, practically insoluble in ethanol 96 per cent. It dissolves in its water of crystallization at about 49C.
IDENTIFICATION
A. It decolorizes iodinated potassium iodide solution.
B. To 0.5 ml of solution S (see Tests) add 0.5 ml of water R and 2 ml of silver nitrate solution. A white precipitate is formed which rapidly becomes yellowish and then black.
C. To 2.5 ml of solution S add 2.5 ml of water and 1 ml of hydrochloric acid. A precipitate of sulphur is formed and gas is evolved which gives a blue colour to starch iodate paper.
D. 1 ml of solution S gives reaction of sodium.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water R prepared from distilled water R and dilute to 100 ml with the same solvent.
Appearance of solution: The freshly prepared solution is clear and colourless.
Dissolve 10.0 g in 50 ml of distilled water, add 1 ml of 0.1 M sodium hydroxide and dilute to 100 ml with the same solvent.
pH: 6.0 to 8.4 for the freshly prepared solution S.
Sulphates and sulphites: Maximum 0.2 per cent.
Sulphides: To 10 ml of solution S add 0.05 ml of a freshly prepared 50 g/l solution of sodium nitroprusside. The solution does not become violet.
Heavy metals: Maximum 10 ppm.
Sodium Thiosulfate FCC Food Grade Specifications
Sodium Thiosulfate
Sodium Hyposulfite
Na2S2O3-5H2O Formula weight 248.19
DESCRIPTION
Sodium Thiosulfate or Sodium Thiosulphate occurs as large, colorless crystals or as a coarse, crystalline powder. It is deliquescent in moist air and effloresces in dry air at a temperature above 33°. Its solutions are neutral or faintly alkaline to litmus. One gram dissolves in 0.5 mL of water. It is insoluble in alcohol.
Function: Sequestrant; antioxidant.
REQUIREMENTS
Identification
A. Add a few drops of iodine TS to a 1:10 aqueous solution. The color disappears.
B. A 1:20 aqueous solution gives positive tests for Sodium and for Thiosulfate.
Assay: Not less than 99.0% and not more than 100.5% of Na2S2O3 after drying.
Lead: Not more than 2 mg/kg.
Selenium: Not more than 0.003%.
Water: Between 32.0% and 37.0%.
Sodium Thiosulfate Pentahydrate Sodium Thiosulphate Analytical Reagent
Na2S2O3-5H2O
Formula Weight 248.19
CAS Number 10102-17-7
REQUIREMENTS
Assay: 99.5-101.0% Na2S2O3-5H2O
pH of a 5% solution: 6.0-8.4 at 25C
MAXIMUM ALLOWABLE
Insoluble matter: 0.005%
Nitrogen compounds (as N): 0.002%
Sulfate and sulfite (as SO4): 0.1%
Sulfide (S): Passes test.
Specifications of Sodium Thiosulfate Anhydrous surpassing all grades including Reagent Grade Standards:
Description: It appears as white powder free from foreign particles.
Solubility: 10% aqueous solution: Freely soluble in water.
Identification:
(A)Reaction of Sodium
(B)Reaction of Thiosulphate
A solution responds to the test for Sodium and for Thiosulphate
Insoluble Matter: Not more than 0.25%
Calcium: Prescribed Test. No turbidity is produced.
pH: 6 to 8.4
Sulphites and Sulphates: Maximum 0.5%
Heavy Metals: Maximum 0.001%
Sodium Sulphite: Maximum 0.5%
Iron as Fe: Not more than 0.001%
Residual Solvent: To meet the requirement
Assay: Not less than 99% and not more than 100.5% of Na2S2O3 on anhydrous basis.
The Uses of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous:
Sodium thiosulfate (STS) is an industrial chemical which also has a long medical history. It was originally used as an intravenous medication for metal poisoning. It has since been approved for the treatment of certain rare medical conditions. These include cyanide poisoning, calciphylaxis, and cisplatin toxicity. It is used for the dechlorination of small water bodies like ponds, aquariums, etc.
The MSDS-SDS Hazard Statement of Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous:
Sodium Thiosulfate Pentahydrate and Anhydrous SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 28-Jan-23
1. Product Identification
Product Name & Other Names: Sodium thiosulfate or Thiosulfuric acid disodium salt or Sodium thiosulphate or Hypo.
CAS No.: 10102-17-7 for pentahydrate and 7772-98-7 for anhydrous
EINECS: EC Number: 231-867-5
Molecular Weight: 248.18 for pentahydrate and 158.11 for anhydrous
Chemical Formula: Na2S2O3-5H2O for pentahydrate and Na2S2O3 for anhydrous
Relevant uses and uses advised against (if any): Industrial Manufacturing.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Sodium thiosulfate or Thiosulfuric acid disodium salt or Sodium thiosulphate or Hypo.
CAS No.: 10102-17-7 for pentahydrate and 7772-98-7 for anhydrous
EINECS: EC Number: 231-867-5
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Note to Physician: Symptomatic and supportive treatment is recommended.
5. Fire Fighting Measures
Flammability of the Product: May pose a fire hazard when exposed to elevated temperatures or by contact with an ignition source.
Products of Combustion: It emits toxic oxides of carbon and oxides of sulfur when heated to decomposition.
Explosion: An explosion may occur if triturated with nitrates, chlorates, or permanganates. Fine dust dispersed in air and in the presence of an ignition source may pose dust explosion hazard.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. Use means suitable for extinguishing surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, nitric acid, fluoride, sodium and potassium nitrate, strong oxidizers, mercury, chlorine, iodine and diketene.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White crystals or powder or granules.
Odor: None
Odor threshold: Not available.
pH: 6-9 at 1% solution at 25 C (77F)
Relative density: Not available.
Melting Point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Readily soluble in water
Viscosity: Not available.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage. Avoid heat and moisture.
Hazardous Decomposition Products: It emits toxic oxides of carbon and oxides of sulfur hydrogen sulfide along with sodium oxide when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Nitric acid, fluoride, sodium and potassium nitrate, strong oxidizers, mercury, chlorine, iodine and diketene.
Conditions to Avoid: Moisture, Heat, Incompatibles.
11. Toxicological Information
Toxicity to Animals:
LD50 Oral - rat - > 8.000 mg/kg on anhydrous basis.
LD50 Intraperitoneal - mouse - 5.200 mg/kg
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
Toxicity to fish: LC50 - Gambusia affinis (Mosquito fish) - 24.000 mg/l - 96 h on anhydrous basis.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: Not likely to bioaccumulate.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IMDG/IMO: Not controlled.
ICAO/ IATA: Not controlled.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California Prop 65: Not listed.
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Structure
CAS Number 10102-17-7 Pentahydrate and 7772-98-7 Anhydrous, Sodium Thiosulfate or Sodium Thiosulphate Pentahydrate Anhydrous Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 13-nov-24
We manufacture:
Copper Sulfate or Cupric Sulphate
Fluorescein Sodium or Fluorescein Disodium
Hydrated Manganese Glycerophosphate