CAS Number Anhydrous 137-40-6 & Hydrate 6700-17-0, Sodium Propionate Anhydrous Hydrate USP NF BP Ph Eur FCC Food Grade Manufacturers Exporters
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CAS Number Anhydrous 137-40-6 & Hydrate 6700-17-0, Sodium Propionate Anhydrous Hydrate Manufacturer Exporter
For Properties Specifications of Sodium Propionate Anhydrous Hydrate Click Properties, Specifications of Sodium Propionate Anhydrous Hydrate Manufacturer.
For Uses of Sodium Propionate Anhydrous Hydrate Click Uses of Sodium Propionate Anhydrous Hydrate Manufacturer.
For For SDS MSDS Sheet of Sodium Propionate Anhydrous Hydrate Click SDS Safety Data Sheet MSDS Sheet of Sodium Propionate Anhydrous Hydrate Manufacturer.
The Properties and Specifications of Sodium Propionate Anhydrous Hydrate:
Sodium Propionate USP NF Grade Specifications
Sodium Propionate
C3H5NaO2·xH2O
Propanoic acid, sodium salt, hydrate.
Sodium propionate hydrate CAS 6700-17-0
Anhydrous 96.06 CAS 137-40-6
Sodium Propionate, dried at 105 for 2 hours, contains not less than 99.0 percent and not more than 100.5 percent of C3H5NaO2.
Identification:
A: Infrared Absorption 197K , on un-dried specimen.
B: A solution (1 in 20) responds to the tests for Sodium.
Alkalinity: Dissolve 2.0 g in 20 mL of water, and add phenolphthalein TS: if a pink color is produced, it is discharged by 0.60 mL of 0.10 N sulfuric acid.
Water: not more than 1.0%.
Heavy metals: Dissolve 2 g in 1 mL of 1 N acetic acid and sufficient water to make 25 mL: the limit is 0.001%.
Sodium Propionate BP Ph Eur Grade Specifications
C3H5NaO2
96.1 -- CAS 137-40-6
Action and use: Antifungal
DEFINITION
Sodium propionate
Content: 99.0 per cent to 101.0 per cent Sodium propionate (dried substance).
CHARACTERS
Appearance: Colourless crystals or, white or almost white powder, slightly hygroscopic.
Solubility: Freely soluble in water, sparingly soluble in alcohol, practically insoluble in methylene chloride.
IDENTIFICATION
First identification A, D.
Second identification B, C, D.
A. Infrared absorption spectrophotometry.
Comparison reference spectrum of sodium propionate.
B. Dissolve 0.1 g in a mixture of 2 ml of copper sulphate solution and 2 ml of methylene chloride. Shake vigorously and allow to stand. Both the upper and the lower layer show a blue colour.
C. To 5 ml of solution S add 2 ml of 0.1 M silver nitrate. A white precipitate is formed.
D. Solution S gives reaction of sodium.
TESTS
Solution S: Dissolve 10 g Sodium propionate in carbon dioxide-free water prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: 7.8 to 9.2
Dilute 1 ml of solution S to 5 ml with water.
Related substances: Liquid chromatography.
Test solution: Dissolve 0.250 g of the substance to be examined in water and dilute to 100 ml with the same solvent.
Reference solution (a) Dissolve 10 mg of the substance to be examined and 10 mg of sodium acetate in water and dilute to 100 ml with the same solvent.
Reference solution (b) Dilute 1.0 ml of the test solution to 100 ml with water.
Column: ı
ı— size: l= 0.25 m, Ø = 4.6 mm;
ı— stationary phase: octadecylsilyl silica gel for chromatography (5μm).
Mobile phase Dilute 1 ml of phosphoric acid R to 1000 ml with water.
Flow rateı1 ml/min.
Detection Spectrophotometer at 210 nm.
Injectionı20 μl.
System suitability Reference solution (a):
ı— resolution: minimum 5 between the peaks due to sodium acetate and sodium propionate.
Limits:
— any impurity: not more than 0.1 times the area of the principal peak in the chromatogram obtained with reference solution (b) (0.1 per cent);
— total: not more than half the area of the principal peak in the chromatogram obtained with reference solution (b) (0.5 per cent);
— disregard limit: 0.05 times the area of the principal peak in the chromatogram obtained with reference solution (b) (0.05 per cent).
Readily oxidizable substances: In a ground-glass-stoppered conical flask introduce 10 g of the substance ( Sodium propionate.) to be examined.
Add 100 ml of water R and stir to dissolve. Add 25 ml of sodium hypobromite solution and 10 ml of a 200 g/l solution of sodium acetate, stopper the flask and allow to stand for 15 min. Add 10 ml of potassium iodide solution and 20 ml of hydrochloric acid while cooling.
Titrate with 0.2 M sodium thiosulphate, adding 2 ml of starch solution R towards the end of the titration. Carry out a blank titration. The difference between the volumes used in the 2 titrations is not greater than 2.2 ml.
Iron: Maximum 10 ppm.
10 ml of solution S complies with the limit test for iron.
Heavy metals: Maximum 10 ppm.
12 ml of solution S complies with limit test A. Prepare the standard using lead standard solution (1 ppm Pb).
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by heating in an oven at 105C for 3 h.
Sodium Propionate FCC Food Grade Specifications
Sodium Propionate
CH3CH2COONa
C3H5NaO2 Formula weight 96.06
INS: 281 CAS 137-40-6
DESCRIPTION
Sodium Propionate occurs as white or colorless, transparent crystals or as a granular, crystalline powder. It is hygroscopic in moist air. One gram is soluble in about 1 mL of water at 25C, in about 0.65 mL of boiling water, and in about 24 mL of alcohol. The pH of a 1:10 aqueous solution is between 8.0 and 10.5.
Function: Preservative; mold inhibitor.
REQUIREMENTS
Identification:
A. A 1:20 aqueous solution gives positive tests for Sodium.
B. Upon ignition, a sample yields an alkaline residue that effervesces with acids.
C. Warm a small sample with sulfuric acid. Propionic acid, recognized by its odor, evolves.
Assay: Not less than 99.0% and not more than 100.5% of C3H5NaO2 after drying.
Alkalinity (as Na2CO3): Passes test (about 0.15%).
Iron: Not more than 0.003%.
Lead: Not more than 2 mg/kg.
Water: Not more than 1%.
The Uses of Sodium Propionate Anhydrous Hydrate:
Sodium Propionate is used as a food preservative and is represented by the food labeling E number E281 in Europe; it is used primarily as a mold inhibitor in bakery products. It is approved for use as a food additive in the EU, USA and Australia and New Zealand. It has a role as an antifungal drug and a food preservative. In pharmacy, it is used in the treatment of skin fungal infections, usually in combination with calcium propionate.
The MSDS-SDS Hazard Statement of Sodium Propionate Anhydrous Hydrate:
Sodium Propionate MSDS Sheet, Material Safety Data Sheet
Propionic Acid, Sodium Salt Sodium Propionate
Sodium Propionate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 27-Jan-23
1. Product Identification
Product Name & Other Names: Sodium Propionate or Propionic Acid Sodium Salt.
CAS No.: 137-40-6
EINECS EC Number: 205-290-4
Molecular Weight: 96.06
Chemical Formula: CH3CH2COONa
Relevant uses and uses advised against (if any): Industrial Manufacturing.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2B, H320
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Word: Warning
Hazard statements:
H315: Causes skin irritation.
H320: Causes eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+313: If skin irritation occurs: Get medical advice/attention.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Sodium Propionate or Propionic Acid Sodium Salt.
CAS Number: 137-40-6
EINECS EC Number: 205-290-4.
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If a person breathes in large amounts of Sodium Propionate, move the exposed person to fresh air.
Ingestion: If large amounts were swallowed, give water to drink and get medical advice.
Skin Contact: In case of contact with Sodium Propionate, immediately wash skin with plenty of soap and water for at least 15 minutes.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Fire: Not expected to be a fire hazard. However, it can burn at high temperatures.
Fire Extinguishing Media: Use extinguishing media appropriate for surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and fire-extinguishing method according to the surrounding is used.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. Exposure Controls/Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: In general, dilution ventilation is a satisfactory health hazard control for this substance.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to Sodium Propionate is apparent and engineering controls are not feasible, consult an industrial hygienist.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: No information found.
Melting Point: 285C (545F).
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Appreciable (> 10%)
Viscosity: Not available.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
11. Toxicological Information
LD50 Oral - mouse - 6.332 mg/kg
LD50 Dermal - rabbit - 1.640 mg/kg
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
Toxicity to fish: LC50 - Pimephales promelas (fathead minnow) - 4.740 mg/l - 96 h
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Waste must be disposed of in accordance with environmental control regulations.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IATA/ICAO & IMDG/IMO: Not controlled.
15. Regulatory Information
USA:
SARA 311/312: See section 2.
Section 16 - Additional Information
DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
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Sodium Propionate Anhydrous Hydrate Structure
CAS Number Anhydrous 137-40-6 & Hydrate 6700-17-0, Sodium Propionate Anhydrous Hydrate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
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Copyright. 25-nov-24
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