CAS Number 68-04-2 Anhydrous and 6132-04-3 Dihydrate, Sodium Citrate Anhydrous Dihydrate USP IP BP Ph Eur FCC Food Grade Manufacturers Exporters
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CAS Number 68-04-2 Anhydrous and 6132-04-3 Dihydrate, Sodium Citrate Anhydrous Dihydrate Manufacturer Exporter
For Properties Specifications of Sodium Citrate Anhydrous Dihydrate Click Properties, Specifications of Sodium Citrate Anhydrous Dihydrate Manufacturer.
For Uses of Sodium Citrate Anhydrous Dihydrate Click Uses of Sodium Citrate Anhydrous Dihydrate Manufacturer.
For For SDS MSDS Sheet of Sodium Citrate Anhydrous Dihydrate Click SDS Safety Data Sheet MSDS Sheet of Sodium Citrate Anhydrous Dihydrate Manufacturer.
The Properties and Specifications of Sodium Citrate Anhydrous Dihydrate :
Sodium Citrate BP Ph Eur Grade Specifications
Sodium Citrate Ph Eur.
Trisodium Citrate Ph Eur.
C6H5Na3O7-2H2O -- 294.1 -- CAS 6132-04-3
DEFINITION
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or white or almost white, granular crystals, slightly deliquescent in moist air.
Solubility: Freely soluble in water, practically insoluble in ethanol (96 per cent).
IDENTIFICATION
A. To 1 ml of solution S (see Tests) add 4 ml of water. The solution gives the reaction of citrates.
B. 1 ml of solution S gives reaction of sodium.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water R prepared from distilled water R and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 10 ml of solution S add 0.1 ml of PhPh solution. Not more than 0.2 ml of 0.1M hydrochloric acid or 0.1 M sodium hydroxide is required to change the colour of the indicator.
Readily carbonizable substances: To 0.20 g of the powdered substance to be examined add 10 ml of sulphuric acid and heat in a water-bath at 90 ± 1C for 60 min. Cool rapidly. The solution is not more intensely coloured than reference solution.
Chlorides: Maximum 50 ppm.
Oxalates: Maximum 300 ppm.
Sulphates: Maximum 150 ppm.
Heavy metals: Maximum 10 ppm.
Water: 11.0 per cent to 13.0 per cent, determined on 0.300 g. After adding the substance to be examined, stir for 15 min before titrating.
Sodium Citrate IP Grade
We also make IP grade of Sodium Citrate
Sodium Citrate USP Grade Specifications
C6H5Na3O7 (anhydrous) 258.07
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt.
Trisodium citrate (anhydrous) [CAS 68-04-2]
Trisodium citrate dihydrate 294.10 CAS 6132-04-3
Sodium Citrate is anhydrous or contains two molecules of water of hydration. It contains not less than 99.0 percent and not more than 100.5 percent of C6H5Na3O7, calculated on the anhydrous basis.
Identification:
A: A solution (1 in 20) responds to the tests for Sodium and for Citrate.
B: Upon ignition, it yields an alkaline residue which effervesces when treated with 3 N hydrochloric acid.
Alkalinity: A solution of 1.0 g in 20 mL of water is alkaline to litmus paper, but after the addition of 0.20 mL of 0.10 N sulfuric acid no pink color is produced by 1 drop of PhPh.
Water: Dry it at 180 for 18 hours: the anhydrous form loses not more than 1.0%, and the hydrous form between 10.0% and 13.0%, of its weight.
Tartrate: the limit is 0.001%.
Sodium Citrate FCC Food Grade Specifications
Trisodium Citrate
C6H5Na3O7 Formula weight, anhydrous 258.07
C6H5Na3O7-2H2O Formula weight, dihydrate 294.10
INS: 331(iii) CAS: anhydrous CAS 68-04-2
CAS: dihydrate CAS 6132-04-3
DESCRIPTION
Sodium Citrate occurs as colorless crystals or as a white, crystalline powder. It is anhydrous or contains two molecules of water of crystallization. One gram of the dihydrate dissolves in 1.5 mL of water at 25C and in 0.6 mL of boiling water. It is insoluble in alcohol.
REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for Sodium and for Citrate.
Assay: Not less than 99.0% and not more than 100.5% of C6H5Na3O7, calculated on the anhydrous basis.
Alkalinity: Passes test.
Lead: Not more than 2 mg/kg.
Water: Anhydrous: Not more than 1%; Dihydrate: Between 10.0% and 13.0%.
Sodium Citrate Anhydrous is offered with very low moisture content.
The Uses of Sodium Citrate Anhydrous Dihydrate:
Sodium Citrate makes blood and urine more alkaline or less acidic. This helps prevent some kidney stones. It is also used to treat metabolic acidosis, a condition in some people with kidney problems. Sodium citrate is an ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures. It is used in food for flavoring.
The MSDS-SDS Hazard Statement of Sodium Citrate Anhydrous Dihydrate:
Sodium Citrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 24-Jan-23
1. Product Identification
Product Name & Other Names: Sodium Citrate or Citnatin or Citreme or Citrosoedine or Citrosodna or Natrocitral or Trisodium citrate dihydrate or 1,2,3-Propanetricarboxylic acid, 2-hydroxy-trisodium salt dihydrate or Citric acid trisodium salt dihydrate.
CAS No.: anhydrous 68-04-2; CAS: dihydrate 6132-04-3
EINECS: EC Number: 200-675-3
Molecular Weight: anhydrous 258.07; dihydrate 294.10
Chemical Formula: C6H5Na3O7 anhydrous 258.07; C6H5Na3O7-2H2O dihydrate 294.10
Relevant uses and uses advised against (if any): Industrial Manufacturing.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Sodium Citrate or Citnatin or Citreme or Citrosoedine or Citrosodna or Natrocitral or Trisodium citrate dihydrate or 1,2,3-Propanetricarboxylic acid, 2-hydroxy-trisodium salt dihydrate or Citric acid trisodium salt dihydrate.
CAS No.: anhydrous 68-04-2; CAS: dihydrate 6132-04-3
EINECS: EC Number: 200-675-3
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: The product is not reported as combustible. It may ignite at high temperature.
Products of Combustion: It emits toxic oxides of carbon and organic fumes when heated to decomposition.
Fire Extinguishing Media: Water spray. Use means suitable for extinguishing surrounding fire. Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. Exposure Controls/Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White crystals or powder or granules.
Odor: None
Odor threshold: Not available.
pH: 7.5-9 at 1% solution at 25 C (77F)
Relative density: around 1.7
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Readily soluble in water
Viscosity: Not available.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits toxic oxides of carbon along with organic fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents and heat.
Conditions to Avoid: Moisture, Heat, Incompatibles.
11. Toxicological Information
Toxicity to Animals: LD50 oral rat 6730 mg/kg.
Carcinogenicity: Not as human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
EC50: 96h 18000 - 32000 mg/L (Chlorella vulgaris, Fresh Water Algae) for CAS No.: 68-04-2
LC50: 96h 18000-32000mg/L (Poecilia reticulata Fish) for CAS No.: 68-04-2
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controled.
IMDG/IMO: Not controled.
IATA/ICAO: Not controled.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California Prop 65: Not listed.
DSCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
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Sodium Citrate Anhydrous Dihydrate Structure
CAS Number 68-04-2 Anhydrous and 6132-04-3 Dihydrate, Sodium Citrate Anhydrous Dihydrate Manufacturer Exporter
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Copyright. 24-jan-23
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