CAS Number 77-93-0, Triethyl Citrate USP NF BP Ph Eur FCC Food Grade Manufacturers Exporters
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CAS Number 77-93-0, Triethyl Citrate Manufacturer Exporter
For Properties Specifications of Triethyl Citrate Click Properties, Specifications of Triethyl Citrate Manufacturer.
For Uses of Triethyl Citrate Click Uses of Triethyl Citrate Manufacturer.
For For SDS MSDS Sheet of Triethyl Citrate Click SDS Safety Data Sheet MSDS Sheet of Triethyl Citrate Manufacturer.
The Properties and Specifications of Triethyl Citrate:
Specifications of Triethyl Citrate USP NF Grade:
C12H20O7 --- 276.28
DEFINITION
Triethyl Citrate contains NLT 99.0% and NMT 100.5% of C12H20O7 , calculated on the anhydrous basis.
IDENTIFICATION
A. Infrared Absorption
B. The retention time of the major peak of the Sample solution corresponds to that of a similar preparation of USP Triethyl Citrate RS, as obtained in the Assay.
ASSAY
To pass the test by Chromatography.
Acceptance criteria: 99.0% - 100.5% on the anhydrous basis
Specific Gravity: 1.135 - 1.139
Refractive Index: 1.439 - 1.441
Acidity:
Neutralized isopropyl alcohol: To a suitable quantity of isopropyl alcohol add 2 - 3 drops of bromothymol blue and just sufficient 0.10 N sodium hydroxide dropwise to produce a faint blue color. [Note: Prepare Neutralized isopropyl alcohol just prior to use.]
Sample solution: 32.0 g of Triethyl Citrate in 30 mL of Neutralized isopropyl alcohol
Analysis: Add bromothymol blue. Titrate with 0.10 N sodium hydroxide to a faint blue endpoint.
Acceptance criteria: NMT 1.0 mL of 0.10 N sodium hydroxide is required.
Water Determination: NMT 0.25%
Specifications of Triethyl Citrate BP Ph Eur Grade:
C12H20O7 --- 276.3 --- CAS 77-93-0
Action and use: Excipient.
DEFINITION
Triethyl 2-hydroxypropane-1,2,3-tricarboxylate.
Content: 98.5 per cent to 101.0 per cent (anhydrous substance).
CHARACTERS
Appearance: Clear, viscous, colourless or almost colourless, hygroscopic liquid.
Solubility: Soluble in water, miscible with ethanol (96 per cent), slightly soluble in fatty oils.
IDENTIFICATION
First identification: A, B
Second identification: A, C, D
A. Refractive index (see Tests).
B. Infrared absorption spectrophotometry.
Comparison Ph. Eur. reference spectrum of triethyl citrate.
C. It gives the reaction of esters.
D. To 0.5 mL add 5 mL of ethanol (96 per cent) and 4 mL of dilute sodium hydroxide solution. Boil under reflux for about 10 min. 2 mL of the solution gives the reaction of citrates.
TESTS
Appearance: The substance to be examined is clear and not more intensely coloured than reference solution
Acidity: Dilute 10 g with 10 mL of previously neutralised ethanol (96 per cent), add 0.5 mL of bromothymol blue solution. Not more than 0.3 mL of 0.1 M sodium hydroxide is required to change the colour of the indicator to blue.
Refractive index: 1.440 to 1.446.
Related substances: To pass the test by Gas chromatography.
Limits:
-any impurity: for each impurity, maximum 0.2 per cent;
-total: maximum 0.5 per cent;
-disregard limit: 0.04 per cent.
Water: Maximum 0.25 per cent, determined on 1.000 g.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Specifications of Triethyl Citrate FCC Food Grade:
Ethyl Citrate
C12H20O7 Formula weight 276.29
INS: 1519 CAS 77-93-0
DESCRIPTION
Triethyl Citrate occurs as a practically colorless, oily liquid. It is slightly soluble in water but is miscible with alcohol and with ether.
Function: Solvent.
REQUIREMENTS
Assay: Not less than 99.0% and not more than 100.5% of C12H20O7, calculated on the anhydrous basis.
Acidity: (as citric acid) Not more than 0.02%.
Lead: Not more than 2 mg/kg.
Refractive Index: Between 1.439 and 1.443 at 25C; or between 1.440 and 1.444 at 20C.
Specific Gravity: Between 1.135 and 1.139 at 25C.
Water: Not more than 0.25%.
The Uses of Triethyl Citrate:
Triethyl citrate is used in foods as a flavouring agent, solvent and surface-active agent Triethyl citrate is an ester of citric acid. It is a colorless, odorless liquid used as a food additive (E number E1505) to stabilize foams, especially as whipping aid for egg white. It is also used in pharmaceutical coatings and plastics. Triethyl citrate is used as solvent, diluent and fixative by perfumers. It is well accepted as an active ingredient in deodorants and excellent for fragrances.
The MSDS-SDS Hazard Statement of Triethyl Citrate:
Triethyl Citrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 31-Jan-23
1. PRODUCT DESCRIPTION
Product Name & Other Names: Triethyl Citrate.
CAS Number: 77-93-0
EINECS EC Number: 201-070-7
Molecular Weight: 276.28
Molecular Formula: C12H20O7 or HOC(COOC2H5)(CH2COOC2H5)2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
2. HAZARD IDENTIFICATION
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling as per GHS & Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements None |
Signal Words: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product Name & Other Names: Triethyl Citrate.
CAS Number: 77-93-0
EINECS EC Number: 201-070-7
4. FIRST AID MEASURES
Always get medical attention after the first aid is over.
Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.
5. FIREFIGHTING PROCEDURES
Extinguisher Media: Use media suitable to extinguish surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture: Fumes, Carbon oxides.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used.
6. SPILL OR LEAK PROCEDURES
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. SPECIAL PRECAUTIONS
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store cold to warm conditions, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing.
8. SPECIAL PROTECTION INFORMATION
Airborne Exposure Limits: None established. Ensure adequate ventilation. Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels low.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. PHYSICAL DATA
Appearance and Odor: Clear colorless or almost colorless oily liquid.
Odor: Odorless.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.14
Melting point/freezing point: -55C literature.
Initial boiling point and boiling range: 294C literature.
Flash point: 151C literature.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Soluble in water, miscible with ethanol (96 per cent).
Viscosity: Not available.
10. REACTIVITY DATA
Stability: It is stable
Conditions to Avoid: Heat, humidity, Dust generation.
Incompatibility (Materials to Avoid): Strong oxidizing.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization: Will not occur
11. TOXICITY DATA
Acute toxicity:
LD50 Oral - Rat - 5.900 mg/kg.
LD50 Dermal - Rabbit - > 5.000 mg/kg.
Carcinogenicity: This product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP, ACGIH & OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. ECOLOGICAL DATA
Toxicity to fish: No information available.
Toxicity to daphnia and other aquatic invertebrates: Immobilization EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h.
Toxicity: Avoid release into the environment.
Persistence and Degradability: Soluble in water Persistence is unlikely based on information available.
Mobility: Will likely be mobile in the environment due to its water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. DISPOSAL INFORMATION
Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations.
14. TRANSPORT INFORMATION
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IMDG/IMO: Not controlled.
IATA: Not controlled.
15. REGULATORY INFORMATION
USA:
SARA 311/312 Hazard Categories: See section 2.
California Proposition 65: Noy listed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is an off-shoot of Anmol Chemicals Taloja. It is located in MIDC Taloja and it is manufacturing pharmaceutical grades of API, Excepients, Food grade and Reagent grade chemicals. Anmol Chemicals & Pharmaceuticals Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies for actual users, retail or small pack supplies for research and development chemicals, fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, Analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals, Mineral Fortifiers at best prices.
Triethyl Citrate Structure
CAS Number 77-93-0, Triethyl Citrate Manufacturer Exporter
ANMOL CHEMICALS & PHARMACEUTICALS Pvt. Ltd.
India, USA, Europe, UAE
TELEPHONE: +912223770100
Navi Mumbai, INDIA
e-mail: info(At the rate i.e. @)anmol.org
Copyright. 1-feb-23
We manufacture:
TBHQ Tertiary Butylhydroquinone